8.00894

N-Ethyldiisopropylamine

for synthesis

• Sinonimo/i: N-Ethyldiisopropylamine, N,N-Diisopropylethylamine
• Formula condensata: [(CH₃)₂CH]₂NCH₂CH₃
• Numero CAS: 7087-68-5
• Peso molecolare: 129.24
• Numero MDL: MFCD00008868
• Codice UNSPSC: 12352116
• Numero indice EU: 230-392-0
• NACRES: NA.22

Proprietà

• Tensione di vapore: 14 hPa ( 20 °C)
• Livello qualitativo: 200
• Saggio: ≥98% (GC)
• Forma fisica: liquid
• Temp. autoaccensione: 240 °C
• Potenza: 200-500 mg/kg LD₅₀, oral (Rat)
• Limite di esplosione: 0.7-6.3 % (v/v)
• pH: 12.3 (20 °C in H₂O, as an emulsion)
• kinematic viscosity: 0.88 cSt(20 °C)
• P. eboll.: 127 °C/1013 hPa
• Temp. transizione: flash point 9.5 °C
• Densità: 0.76 g/cm³ at 20 °C
• Temperatura di conservazione: 2-30°C
• InChI: 1S/C8H19N/c1-6-9(7(2)3)8(4)5/h7-8H,6H2,1-5H3; JGFZNNIVVJXRND-UHFFFAOYSA-N

Descrizione

Descrizione generale

N,N-Diisopropylethylamine (DIPEA), also known as Hunig′s base, is a sterically hindered amine. It is a non-nucleophilic base commonly employed in substitution reactions, alkylations, amide couplings, etc. DIPEA is also used as a base in the Pd-catalyzed cross-coupling reactions, which include Heck coupling and Sonagashira coupling reactions.

Applicazioni

• Dual Stimuli-Responsive Hybrid Polymeric Nanoparticles Self-Assembled from POSS-Based: Describes the synthesis of hybrid polymeric nanoparticles using N-Ethyldiisopropylamine in the assembly process (Yang et al., 2022).
• Magnetical Control of the Charge-Separated State Lifetime Realized by Covalent Attachment of a Platinum Complex: Details the use of N-Ethyldiisopropylamine in the preparation of magnetically controllable platinum complexes (Kozaki et al., 2021).
• Hybrid block copolymers of polyesters/polycarbonates and polypeptides synthesized via one-pot sequential ring-opening polymerization: Explains the initiation of polymerization with N-Ethyldiisopropylamine for creating hybrid block copolymers (Gradišar et al., 2018).

Risultati analitici

Assay (GC, area%): ≥ 98.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.755 - 0.758
Water (K. F.): ≤ 0.20 %
Identity (IR): passes test

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS05,GHS06,GHS09
• Avvertenze: Danger
• Indicazioni di pericolo: H225 - H302 - H318 - H331 - H335 - H411
• Consigli di prudenza: P210 - P273 - P280 - P301 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): 49.1 °F
• Punto d’infiammabilità (°C): 9.5 °C