330200-M

Ecotin, E. coli

A potent, broad range inhibitor of serine proteases.

• Codice UNSPSC: 12352200
• NACRES: NA.77

Proprietà

• Livello qualitativo: 100
• Saggio: ≥90% (SDS-PAGE)
• Forma fisica: liquid
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze; avoid repeated freeze/thaw cycles
• Temperatura di conservazione: −70°C

Descrizione

Descrizione generale

A potent, broad range inhibitor of serine proteases.

A potent, broad range inhibitor of serine proteases. Exhibits picomolar binding constant for the inhibition of chymotrypsin, elastase, Factor Xa, Factor XIIa, kallikrein, and trypsin. Also acts as an effective inhibitor of collagenase.

A potent, broad range inhibitor or serine proteases. Exhibits picomolar binding constant for the inhibition of chymotrypsin, elastase, Factor Xa, Factor XIIa, kallikrein, and trypsin. Also an effective inhibitor of collagenase and granzyme B.

Azioni biochim/fisiol

Primary Target
serine proteases

Product does not compete with ATP.

Target IC₅₀: 1 pM against serine proteases

binds trypsin in the picomolar range

Confezionamento

Please refer to vial label for lot-specific concentration.

Attenzione

Toxicity: Standard Handling (A)

Stato fisico

In 1.0 mM HCl.

Ricostituzione

Following initial thaw, aliquot and freeze (-70°C).

Altre note

McGrath, M.E., et al. 1995. Protein Sci. 4, 141.
Seong, I.S., et al. 1994. J. Biol. Chem. 269, 21915.
McGrath, M.E., et al. 1991. J. Biol. Chem. 266, 6620.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable