16-246

Anti-EGFR Antibody, neutralizing, clone LA1, Alexa Fluor^™ 488

clone LA1, Upstate^®, from mouse

• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Coniugato: ALEXA FLUOR^™ 488
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: LA1, monoclonal
• Reattività contro le specie: human, mouse, rat
• Produttore/marchio commerciale: Upstate^®
• tecniche: immunofluorescence: suitable
• Isotipo: IgG1
• N° accesso NCBI: NM_005228.3; NM_201282.1; NM_201283.1; NM_201284.1
• N° accesso UniProt: P00533
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... EGFR(1956) ; mouse ... Egfr(13649) ; rat ... Egf(25313)

Descrizione

Descrizione generale

Included Negative Control: Catalog # 16-240, Alexa Fluor^™ 488-conjugated Normal Mouse IgG.

Inhibits A431 cell growth. Recognizes an antigenic determinant located on the extracellular domain of the receptor.

Specificità

external domain of EGF receptor on all human cells. Competes with EGF and TGF-α for binding on human cells. Recognizes both phosphorylated and non-phosphorylated human EGF receptors.

Immunogeno

Human A431 membrane proteins

Applicazioni

Research Category
Signaling

Research Sub Category
Growth Factors & Receptors

This Anti-EGFR Antibody, neutralizing, clone LA1, Alexa Fluor 488 is validated for use in IF for the detection of EGFR.

Qualità

Routinely evaluated by positive immunostaining for the EGF receptor in A431 cells.

Stoccaggio e stabilità

1 year at 4°C from date of shipment

Note legali

ALEXA FLUOR is a trademark of Life Technologies

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Alexa Fluor^™ is a registered trademark of Molecular Probes, Inc.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable