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Merck
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Key Documents

16-189

Sigma-Aldrich

Anti-phospho-Histone H3 (Ser10) Antibody, biotin conjugate

Upstate®, from rabbit

Sinonimo/i:

H3 histone, family 3A, H3S10P, Histone H3 (phospho S10), H3 histone, family 3A, H3 histone, family 3B, H3 histone, family 3B (H3.3B)

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

100

Coniugato

biotin conjugate

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Reattività contro le specie

human

Produttore/marchio commerciale

Upstate®

tecniche

immunocytochemistry: suitable
western blot: suitable

Isotipo

IgG

N° accesso NCBI

NM_003493.2

N° accesso UniProt

Q16695

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

phosphorylation (pSer10)

Informazioni sul gene

human ... HIST1H3F(8968)

Immunogeno

KLH-conjugated peptide (ARK[pS]TGGKAPRKQL- C) corresponding to amino acids 7-20 of human histone H3.

Applicazioni

Anti-phospho-Histone H3 (Ser10) Antibody, biotin conjugate is a Rabbit Polyclonal Antibody for detection of Histone H3 phosphorylated at serine 10. This purified mAb, also known as H3S10p,is biotinylated, published in peer reviewed journals and has been validated in WB, ICC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones

Qualità

routinely evaluated in immunocytochemistry by immunostaining chromatin in HeLa cells undergoing mitosis

Stato fisico

PBS, pH 7.4, with 0.05% sodium azide.
Protein A purified

Stoccaggio e stabilità

6 months at 4°C

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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An-Sofie Stevens et al.
Scientific reports, 7, 45616-45616 (2017-05-04)
One of the major challenges in the development of alternative carcinogenicity assays is the prediction of non-genotoxic carcinogens. The variety of non-genotoxic cancer pathways complicates the search for reliable parameters expressing their carcinogenicity. As non-genotoxic and genotoxic carcinogens have different
An-Sofie Stevens et al.
Toxicological sciences : an official journal of the Society of Toxicology, 162(1), 251-263 (2017-11-18)
Aiming to in vivo characterize the responses of pluripotent stem cells and regenerative tissues to carcinogenic stress, we employed the highly regenerative organism Schmidtea mediterranea. Its broad regenerative capacities are attributable to a large pool of pluripotent stem cells, which
Jason D Gray et al.
Human molecular genetics, 22(21), 4267-4281 (2013-06-19)
Low-density lipoprotein receptor related protein 6 (Lrp6) mutational effects on neurulation were examined using gain (Crooked tail, Lrp6(Cd)) and loss (Lrp6(-)) of function mouse lines. Two features often associated with canonical Wnt signaling, dorsal-ventral patterning and proliferation, were no different
An-Sofie Stevens et al.
Journal of applied toxicology : JAT, 35(3), 319-326 (2014-06-27)
To investigate hydrophobic test compounds in toxicological studies, solvents like dimethylsulfoxide (DMSO) are inevitable. However, using these solvents, the interpretation of test compound-induced responses can be biased. DMSO concentration guidelines are available, but are mostly based on acute exposures involving
Jason D Gray et al.
Human molecular genetics, 19(23), 4560-4572 (2010-09-17)
Crooked tail (Cd) mice bear a gain-of-function mutation in Lrp6, a co-receptor for canonical WNT signaling, and are a model of neural tube defects (NTDs), preventable with dietary folic acid (FA) supplementation. Whether the FA response reflects a direct influence
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