1.37162

D-mannitolo

EMPROVE^® EXPERT, Ph. Eur., BP, ChP, JP, USP

• Sinonimo/i: Mannite
• Formula empirica (notazione di Hill): C₆H₁₄O₆
• Numero CAS: 69-65-8
• Peso molecolare: 182.17
• Beilstein: 1721898
• Numero MDL: MFCD00064287
• Codice UNSPSC: 12352201

Proprietà

• agenzia: BP; ChP; JP; Ph. Eur.; USP
• Livello qualitativo: 500
• Nome Commerciale: EMPROVE^® EXPERT
• Forma fisica: solid
• Impurezze: low in endotoxins
• pH: 5.0-6.5 (120 °C, 182 g/L)
• P. eboll.: 290-295 °C/4.67 hPa
• Punto di fusione: 166-169 °C
• Solubilità: 213 g/L
• applicazioni: liquid formulation; ophthalmics; parenterals; pharma/biopharma processes
• Temperatura di conservazione: 2-25°C
• Stringa SMILE: OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
• InChI: 1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1; FBPFZTCFMRRESA-KVTDHHQDSA-N

Descrizione

Descrizione generale

Chemicals play an important role in the stabilization of a biologic drug during its manufacturing and formulation process – for instance, by preventing aggregation. We offer a wide range of high-quality stabilizers, buffers and salts to successfully purify and formulate your biomolecules. Specifically developed for high-risk applications, they are low in bioburden and endotoxins. As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Applicazioni

Mannitol is a sugar alcohol which is used widely in biomolecule formulations as a stabilizer, bulking agent, and lyoprotecting agent, especially in lyophilization. Due to its low microbial and endotoxin limits, D(-)-Mannitol Emprove^® Expert is especially suitable for high-risk applications.

Azioni biochim/fisiol

Un alcool dal sapore di zucchero dolce. Usato in test di inibizione del sapore dolce.

Note legali

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable