1.11714

3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide

for biochemistry

• Sinonimo/i: 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide, Thiazolyl blue, MTT
• Formula empirica (notazione di Hill): C₁₈H₁₆BrN₅S
• Numero CAS: 298-93-1
• Peso molecolare: 414.32
• Numero MDL: MFCD00011964
• Codice UNSPSC: 12352107
• Numero indice EU: 206-069-5
• NACRES: NA.21

Proprietà

• Livello qualitativo: 100
• Forma fisica: solid
• Punto di fusione: 195 °C
• Solubilità: 10 g/L
• Temperatura di conservazione: 2-30°C
• InChI: 1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1; AZKSAVLVSZKNRD-UHFFFAOYSA-M

Descrizione

Applicazioni

<ul>
<li><strong>Anal Biochem, 2017</strong>: Comparison of MTT and Neutral Red assays to assess cell viability in the presence of copper compounds, highlighting the versatility and sensitivity of the MTT assay in cytotoxicity testing (Gomez Perez et al., 2017).</li>
<li><strong>Indian J Pharmacol, 2016</strong>: Evaluation of the cytotoxic potential of various Indian fruit peels on liver cancer cells (HepG2) using MTT assay, providing insights into natural product research and potential anticancer properties (Garg et al., 2016).</li>
<li><strong>ACS Appl Mater Interfaces, 2015</strong>: Application in the real-time evaluation of live cancer cells, combining surface plasmon resonance and electrochemical methodologies with MTT assays for enhanced accuracy in viability testing (Wu et al., 2015).</li>
</ul>

Risultati analitici

Assay (argentometric): ≥ 98
Identity (IR-spectrum): passes test
Spec. Absorptivity A 1%/1cm (242 nm; 0.001 %; 1 cm; methanol): 480 - 530
Heavy metals (as Pb): ≤ 0.001 %
Sulfated ash: ≤ 0.5 %

Informazioni sulla sicurezza

• Pittogrammi: GHS07,GHS08
• Avvertenze: Warning
• Indicazioni di pericolo: H315 - H319 - H335 - H341
• Consigli di prudenza: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Classi di pericolo: Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable