1.03668

D-Mannitolo

EMPROVE^® EXPERT, Ph. Eur., BP, JP, USP, E 421

• Sinonimo/i: D-Mannitol
• Formula empirica (notazione di Hill): C₆H₁₄O₆
• Numero CAS: 69-65-8
• Peso molecolare: 182.17
• Numero MDL: MFCD00064287
• Codice UNSPSC: 12352107
• Numero E: E421
• Numero indice EU: 200-711-8

Proprietà

• agenzia: BP; JP; Ph. Eur.; USP
• Livello qualitativo: 500
• Nome Commerciale: EMPROVE^® EXPERT
• Forma fisica: fine powder
• Dimensione particelle: 145-200 μm (d50)
• pH: 5-7 (20 °C, 100 g/L in H₂O)
• Punto di fusione: 164-169 °C
• Solubilità: 213 g/L
• applicazioni: liquid formulation; pharmaceutical; solid formulation
• Temperatura di conservazione: 2-25°C
• InChI: 1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2; FBPFZTCFMRRESA-UHFFFAOYSA-N

Descrizione

Descrizione generale

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck^® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Applicazioni

Parteck^® M DPI is a synthetic and versatile carrier option for your dry powder inhalation (DPI) formulation. Engineered from mannitol, Parteck^® M DPI particles are designed to improve the flow and release characteristics of active pharmaceutical ingredients (APIs) in drugs delivered via dry, inhaled powders.
As Emprove^® Expert product, Parteck^® M DPI is specified with low low microbial and endotoxin limits, making is especially suitable for high-risk applications.

Caratteristiche e vantaggi

• Particle distribution designed to improve flow and release characteristics in DPI application
• Low water content & hygroscopicity
• Synthesized from plant-based raw materials
• 3-year shelf life
• High API delivery to the lungs

Note legali

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1