1.05980

D-mannitolo

EMPROVE^® ESSENTIAL, Ph. Eur., BP, ChP, JP, USP, FCC, E 421

• Sinonimo/i: Mannite
• Formula empirica (notazione di Hill): C₆H₁₄O₆
• Numero CAS: 69-65-8
• Peso molecolare: 182.17
• Beilstein: 1721898
• Numero MDL: MFCD00064287
• Codice UNSPSC: 12352201
• Numero E: E421
• Numero indice EU: 200-711-8

Proprietà

• agenzia: BP; ChP; JP; Ph. Eur.; USP
• Livello qualitativo: 500
• Conformità normativa: FCC
• Nome Commerciale: EMPROVE^® ESSENTIAL
• Stato: fine powder
• Temp. autoaccensione: 410 °C
• Potenza: 13500 mg/kg LD₅₀, oral (Rat)
• Qualità: E 421
• Dimensione particelle: (see specification)
• pH: 5-7 (20 °C, 100 g/L in H₂O)
• P. ebollizione: 290-295 °C/4 hPa
• Punto di fusione: 167-170 °C (lit.)
• Solubilità: 213 g/L
• applicazioni: liquid formulation; pharmaceutical; semi-solid formulation; solid formulation
• Temperatura di conservazione: 2-25°C
• Stringa SMILE: OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
• InChI: 1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1; FBPFZTCFMRRESA-KVTDHHQDSA-N

Descrizione

Descrizione generale

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Applicazioni

Mannitol is widely used in pharmaceutical formulations and food applications, mainly as diluent and bulking agent in solid oral formulations such as tablets. For mannitols with DC properties or for a product specifically developed for wet granulation, please explore the Parteck^® range of products.

Azioni biochim/fisiol

Un alcool dal sapore di zucchero dolce. Usato in test di inibizione del sapore dolce.

Note legali

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1