1.01656

Endonucleasi

• Sinonimo/i: Endonuclease from Serratia marcescens
• Numero CAS: 9025-65-4
• Classificazione EC (Enzyme Commission): 3.1.30.2 (BRENDA, IUBMB)
• Numero MDL: MFCD00131010
• Codice UNSPSC: 12352202

Proprietà

• Origine biologica: Serratia marcescens
• Livello qualitativo: 100
• Ricombinante: expressed in E. coli
• Sterilità: non-sterile
• Saggio: ≥90% (SDS-PAGE)
• Forma fisica: buffered aqueous glycerol solution
• Attività specifica: ≥250 units, pH 8.0, 37 °C
• Concentrazione: ≥250 units/μL
• Impurezze: ≤10 CFU in 100 000 U Colony count (Yeasts and moulds); ≤10 CFU in 100 000 U Colony count (aerobic bacteria); not detectable Proteases
• Colore: clear; colorless
• pH: 8 (25 °C in H₂O)
• applicazioni: pharma/biopharma processes
• Attività estranea: foreign activity ≥1.0 x 10^6 units (calc. on protein)
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

Our comprehensive portfolio of downstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

We offer a range of high quality critical raw materials plus the documentation and expertise to help our customers meet stringent regulatory requirements. Our SAFC^® portfolio of high-quality products withstands strict quality control procedures.

Applicazioni

Benzonase^® purity grade II (>90%) for biotechnology is the technical grade in our Benzonase^® product portfolio. All Benzonase^® endonuclease products share the same amino acid sequence (proven by LC-MS/MS mass spectrometry), robustness and activity. The technical grade can be used to optimize the production / testing process before using one of our GMP grade during verification and manufacturing process.

Utilizzato per rimuovere gli acidi nucleici dai campioni di proteine.

Azioni biochim/fisiol

Digerisce DNA ed RNA nativi o denaturati con calore.

Confezionamento

500,000 Units5,000,000 Units

Note legali

Benzonase is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1