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Merck
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Documenti fondamentali

07-328

Sigma-Aldrich

Anti-acetyl-Histone H4 (Lys8) Antibody

serum, Upstate®

Sinonimo/i:

H4K8Ac, Histone H4 (acetyl K8)

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

100

Forma dell’anticorpo

serum

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Reattività contro le specie

human, Saccharomyces cerevisiae

Produttore/marchio commerciale

Upstate®

tecniche

ChIP: suitable (ChIP-seq)
dot blot: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotipo

IgG

N° accesso NCBI

NM_175054

N° accesso UniProt

P62805

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

acetylation (Lys8)

Informazioni sul gene

human ... H4C1(8359)

Descrizione generale

Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H4 is involved with the structure of the nucleosomes of the ′beads on a string′ structure.



The N-terminal tail of histone H4 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Immunogeno

Peptide corresponding to amino acids 3-13 of yeast Histone H4 (RGKGGAcKGLGKG-C) in which lysine 8 is acetylated.

Applicazioni

Use Anti-acetyl-Histone H4 (Lys8) Antibody (Rabbit Polyclonal Antibody) validated in ChIP, IP, WB, DB, ChIP-seq to detect acetyl-Histone H4 (Lys8) also known as H4K8Ac, Histone H4 (acetyl K8).

Qualità

routinely evaluated by immunoblot on acid extracts from sodium butyrate treated HeLa cells

Descrizione del bersaglio

10 kDa

Risultati analitici

Control
Sodium butyrate treated HeLa cells

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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