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N-051

Supelco

Nalbuphine hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Formula empirica (notazione di Hill):
C21H28ClNO4
Numero CAS:
23277-43-2
Peso molecolare:
393.90
Codice UNSPSC:
41116107
NACRES:
NA.24

Grado

certified reference material

Forma fisica

liquid

Caratteristiche

Snap-N-Spike®/Snap-N-Shoot®

Confezionamento

ampule of 1 mL

Produttore/marchio commerciale

Cerilliant®

Concentrazione

1.0 mg/mL in methanol (as free base)

tecniche

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

applicazioni

forensics and toxicology

Formato

single component solution

Temperatura di conservazione

−20°C

Stringa SMILE

Cl.O[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC6CCC6)c45

InChI

1S/C21H27NO4.ClH/c23-14-5-4-13-10-16-21(25)7-6-15(24)19-20(21,17(13)18(14)26-19)8-9-22(16)11-12-2-1-3-12;/h4-5,12,15-16,19,23-25H,1-3,6-11H2;1H/t15-,16+,19-,20-,21+;/m0./s1
YZLZPSJXMWGIFH-BCXQGASESA-N

Informazioni sul gene

human ... OPRD1(4985) , OPRK1(4986) , OPRM1(4988)

Descrizione generale

A Snap-N-Spike® reference solution applicable for use in urine drug testing, pain prescription monitoring, clinical toxicology, forensic analysis, or pharmaceutical research by LC-MS/MS or GC/MS. Nalbuphine is a semisynthetic opioid analgesic sold under the trade name Nubain®. This painkiller is prescribed for the relief of moderate to severe pain.

Applicazioni


  • Development of a Thin-Layer Chromatography-Enzymatic Test Combination Method for the Isolation of α-Glucosidase Inhibitors From Thymelaea hirsuta.: Abid et al. (2022) combined thin-layer chromatography and enzymatic tests using Silica gel 60 TLC plates to isolate α-glucosidase inhibitors from Thymelaea hirsuta, showcasing a novel method for biochemical studies (Abid et al., 2022).

  • HPLC-UV and TLC-Densitometry Methods for Simultaneous Determination of Sofosbuvir and Daclatasvir: Application to Darvoni Tablet.: Fayed et al. (2022) utilized Silica gel 60 TLC plates in their TLC-densitometry method for the simultaneous determination of sofosbuvir and daclatasvir in pharmaceutical tablets, demonstrating the method′s application in pharmaceutical analysis (Fayed et al., 2022).


Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Nubain is a registered trademark of Endo Pharmaceuticals Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Avvertenze

Danger

Indicazioni di pericolo

H225,H301 + H311 + H331,H370

Classi di pericolo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organi bersaglio

Eyes

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

49.5 °F - closed cup

Punto d’infiammabilità (°C)

9.7 °C - closed cup

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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S Sultana et al.
Drug research, 63(5), 224-227 (2013-03-15)
The interaction of nalbuphine hydrochloride with calf thymus deoxyribonucleic acid was investigated by absorption and fluorescence titration techniques. Hypochromic effect was observed in the absorption spectra of nalbuphine. The fluorescence quenching of nalbuphine by DNA was found to be static
David Sanchez-Migallon Guzman et al.
American journal of veterinary research, 72(6), 736-740 (2011-06-02)
To evaluate the antinociceptive effects and duration of action of nalbuphine HCl administered IM on thermal thresholds in Hispaniolan Amazon parrots (Amazona ventralis). 14 healthy adult Hispaniolan Amazon parrots of unknown sex. 3 doses of nalbuphine (12.5, 25, and 50
Jason S Clark et al.
Veterinary ophthalmology, 14(6), 358-364 (2011-11-05)
To evaluate the effectiveness of topical nalbuphine or oral tramadol in the treatment of corneal pain in dogs. Fourteen male Beagle dogs. Dogs were divided into three treatment groups and sedated with dexmedetomidine (5 μ/kg IV). A 4 mm corneal
David Sanchez-Migallon Guzman et al.
American journal of veterinary research, 74(2), 191-195 (2013-02-01)
To evaluate the pharmacokinetics of nalbuphine decanoate after IM administration to Hispaniolan Amazon parrots (Amazona ventralis). 9 healthy adult Hispaniolan Amazon parrots of unknown sex. Nalbuphine decanoate (37.5 mg/kg) was administered IM to all birds. Plasma samples were obtained from
Chrystelle Sola et al.
Paediatric anaesthesia, 22(9), 841-846 (2012-05-17)
Bilateral suprazygomatic maxillary nerve blocks approach improves pain relief after palate surgery. We report the feasibility and efficiency of ultrasound-guided suprazygomatic maxillary nerve blocks in cleft palate repair in children. Twenty-five children scheduled to undergo surgical cleft palate repair were
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