890704C

18:1 EPC (Cl Salt)

Avanti Research^™ - A Croda Brand 890704C

• Sinonimo/i: 1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (chloride salt)
• Formula empirica (notazione di Hill): C₄₆H₈₉NO₈PCl
• Numero CAS: 474945-24-9
• Peso molecolare: 850.63
• Codice UNSPSC: 12352211
• NACRES: NA.25

Proprietà

• Forma fisica: liquid
• Confezionamento: pkg of 1 × 2.5 mL (890704C-25mg); pkg of 1 × 4 mL (890704C-100mg); pkg of 2 × 4 mL (890704C-200mg)
• Produttore/marchio commerciale: Avanti Research^™ - A Croda Brand 890704C
• Concentrazione: 10 mg/mL (890704C-25mg); 25 mg/mL (890704C-100mg); 25 mg/mL (890704C-200mg)
• Tipo di lipide: transfection; cationic lipids
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• Stringa SMILE: O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)OCC.[Cl-]

Descrizione

Descrizione generale

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (18:1 EPC) is a cationic alkylated phospholipid.

Applicazioni

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (chloride salt) (18:1 EPC (Cl Salt)) is suitable:

• for composing lipid shell to prepare lipopolyplex/mRNA vaccine
• in solvent-assisted preparation of supported lipid bilayers
• along with 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE) in mixed liposomes as colloidal vectors for physicochemical study of the DNA compaction
• to formulate the lipid nanoparticle (LNP1) to enhance intracellular delivery mediated by shock waves

Azioni biochim/fisiol

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (18:1 EPC) serves as a transfection reagent. 18:1 EPC is applicable in liposomes and lipoplexes. It is a potential vector in gene therapy.

Confezionamento

5 mL Clear Glass Sealed Ampule (890704C-100mg)

5 mL Clear Glass Sealed Ampule (890704C-200mg)

5 mL Clear Glass Sealed Ampule (890704C-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H315,H319,H331,H336,H351,H361d,H372
• Consigli di prudenza: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Classi di pericolo: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Organi bersaglio: Liver,Kidney, Respiratory system
• Codice della classe di stoccaggio: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): does not flash
• Punto d’infiammabilità (°C): does not flash