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878112C

Avanti

C16-18:1 PC

Avanti Research™ - A Croda Brand 878112C

Sinonimo/i:

1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine

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About This Item

Formula empirica (notazione di Hill):
C42H84NO7P
Numero CAS:
95403-34-2
Peso molecolare:
746.09
Numero MDL:
MFCD11974148
Codice UNSPSC:
12352211
NACRES:
NA.25

Stato

liquid

Confezionamento

pkg of 1 × 1 mL (878112C-5mg)

Produttore/marchio commerciale

Avanti Research™ - A Croda Brand 878112C

Concentrazione

5 mg/mL (878112C-5mg)

Tipo di lipide

phosphoglycerides
bioactive lipids

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COCCCCCCCCCCCCCCCC)=O

InChI

SIEDNCDNGMIKST-IYEJTHTFSA-N

Descrizione generale

C16-18:1 PC, also referred as 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine (HOPC), is a platelet activating factor. It belongs to the class of bioactive lipids. HOPC is a mono-ether PC containing ester-linked 18:1 chain (oleoyl) at the sn-2 position and an ether-linked 16:0 chain (hexadecyl) at the sn-1 position.

Applicazioni

C16-18:1 PC or 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine may be used: as a lipid standard for quantification of glycerophosphocholine by liquid chromatography–mass spectrometry (LC–MS), in preparation of phospholipid vesicles, as a substrate to study the substrate specificity of phospholipase B/lipase (PLB/LIP) in the presence and absence of deoxycholate (DOC).

Azioni biochim/fisiol

Platelet-activating factor (PAF) acts as a lipid mediator and is involved in various inflammatory diseases.

Confezionamento

5 mL Clear Glass Sealed Ampule (878112C-5mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Classi di pericolo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Organi bersaglio

Central nervous system, Liver,Kidney

Classe di pericolosità dell'acqua (WGK)

WGK 3

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Certificati d'analisi (COA)

Lot/Batch Number

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Matts Nylund et al.
Biochimica et biophysica acta, 1758(6), 807-812 (2006-06-17)
The glycolipid transfer protein (GLTP)-mediated movement of galactosylceramide from model membrane donor vesicles to acceptor vesicles is sensitive to the membrane environment surrounding the glycolipid. GLTP can catalyze the transfer of a fluorescently labeled GSL, anthrylvinyl-galactosylceramide (AV-GalCer), from vesicles composed
Akira Sato et al.
European journal of pharmacology, 745, 46-51 (2014-12-03)
Platelet-activating factor (PAF) is a potent lipid mediator that is implicated in numerous inflammatory diseases. C-reactive protein (CRP) is an acute-phase plasma protein that increases rapidly and dramatically in response to inflammation. In this study, we investigated the effect of
John J H Shin et al.
Developmental cell, 52(4), 461-476 (2020-01-14)
Phosphoinositides, diacylglycerolpyrophosphate, ceramide-1-phosphate, and phosphatidic acid belong to a unique class of membrane signaling lipids that contain phosphomonoesters in their headgroups having pKa values in the physiological range. The phosphomonoester headgroup of phosphatidic acid enables this lipid to act as

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