700016P

cholesterol sulfate

Avanti Research^™ - A Croda Brand 700016P

• Sinonimo/i: cholesterol sulfonate; cholesteryl sulfate; sodium cholesteryl sulfate; cholesteryl sulphate
• Formula empirica (notazione di Hill): C₂₇H₄₅NaO₄S
• Numero CAS: 2864-50-8
• Peso molecolare: 488.70
• Numero MDL: MFCD00079091
• Codice UNSPSC: 12352211
• NACRES: NA.25

Proprietà

• Descrizione: cholesterol 3-sulfate (sodium salt)
• Saggio: >99% (TLC)
• Stato: powder
• Confezionamento: pkg of 1 × 1 g (700016P-1g); pkg of 1 × 25 mg (700016P-25mg); pkg of 1 × 500 mg (700016P-500mg)
• Produttore/marchio commerciale: Avanti Research^™ - A Croda Brand 700016P
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• Stringa SMILE: [Na+].[S](=O)(=O)([O-])O[C@H]1CC[C@@]2([C@@H]3[C@H]([C@H]4[C@@]([C@H](CC4)[C@@H](CCCC(C)C)C)(CC3)C)CC=C2C1)C
• InChI: 1S/C27H46O4S.Na/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(31-32(28,29)30)13-15-26(20,4)25(22)14-16-27(23,24)5;/h9,18-19,21-25H,6-8,10-17H2,1-5H3,(H,28,29,30);/q;+1/p-1/t19-,21+,22+,23-,24+,25+,26+,27-;/m1./s1; LMPVQXVJTZWENW-KPNWGBFJSA-M

Descrizione

Descrizione generale

Cholesterol sulfate is synthesized by the sulfoconjugation of cholesterol in the presence of enzyme cholesterol sulfotransferase. It is present in brain, lungs, hair and skin tissues as well as cells including erythrocytes, platelets and spermatozoa.

Applicazioni

Cholesterol sulfate has been used in micelle preparation and in surface plasmon resonance (SPR) studies.

Azioni biochim/fisiol

Cholesterol sulfate is associated with atherosclerotic lesions and serves as a substrate for platelet adhesion. It stabilizes the spermatozoa membranes and erythrocytes. Cholesterol sulfate is involved in the keratinocyte differentiation and its levels are elevated in recessive X-linked ichthyosis. It serves as a ligand for retinoic acid-related orphan receptor α (RORα). Cholesterol sulfate regulates glucose metabolism and is a potential target for metabolic disorders. It is also a potential marker for human uterine cervical carcinoma tissue and prostate carcinoma.

Confezionamento

20 mL Clear Glass Screw Cap Vial (700016P-1g)

20 mL Clear Glass Screw Cap Vial (700016P-500mg)

5 mL Amber Glass Screw Cap Vial (700016P-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable