W297607

Quinine monohydrochloride dihydrate

≥95%, FG

• Sinonimo/i: Quinine monohydrochloride dihydrate, Quinine hydrochloride dihydrate
• Formula empirica (notazione di Hill): C₂₀H₂₄N₂O₂ · HCl · 2H₂O
• Numero CAS: 6119-47-7
• Peso molecolare: 396.91
• Numero FEMA: 2976
• Beilstein: 6112655
• Numero CE: 205-001-1
• N° CoE: 715
• Numero MDL: MFCD00151248
• Codice UNSPSC: 12164502
• ID PubChem: 24901428
• Numero Flavis: 14.155
• NACRES: NA.21

Proprietà

• Origine biologica: synthetic
• Livello qualitativo: 400
• Grado: FG; Halal; Kosher
• Conformità normativa: EU Regulation 1334/2008 & 872/2012
• Saggio: ≥95%
• Attività ottica: [α]22/D −235°, c = 2 in 0.1 M HCl
• Punto di fusione: 115-116 °C (dec.) (lit.)
• applicazioni: flavors and fragrances
• Documentazione: see Safety & Documentation for available documents
• Allergene alimentare: no known allergens
• Organolettico: odorless
• Stringa SMILE: Cl[H].[H]O[H].[H]O[H].[H][C@@]12CCN(C[C@@H]1C=C)[C@@]([H])(C2)[C@H](O)c3ccnc4ccc(OC)cc34
• InChI: 1S/C20H24N2O2.ClH.2H2O/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;;;/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;1H;2*1H2/t13-,14-,19-,20+;;;/m0.../s1; MPQKYZPYCSTMEI-FLZPLBAKSA-N

Descrizione

Applicazioni

• Rats can predict aversiveness of Active Pharmaceutical Ingredients.: This study explores the use of rats to predict the aversiveness of various active pharmaceutical ingredients (APIs), including Quinine hydrochloride dihydrate, by measuring behavioral responses. The findings suggest that animal models can be effective in preclinical assessments of API aversiveness, which is crucial for drug formulation and patient compliance (Soto et al., 2018).


• Impact of sodium lauryl sulfate in oral liquids on e-tongue measurements.: This research investigates the influence of sodium lauryl sulfate on electronic tongue measurements of bitterness in oral liquid formulations containing Quinine hydrochloride dihydrate. The study highlights the importance of excipients in modifying taste perception, which is significant for developing palatable pharmaceutical products (Immohr et al., 2016).

Informazioni sulla sicurezza

• Pittogrammi: GHS08,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H317,H334
• Consigli di prudenza: P261 - P264 - P272 - P280 - P301 + P312 - P302 + P352
• Classi di pericolo: Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Faceshields, Gloves