QBD10502

Azido-dPEG^®₄-acid

• Sinonimo/i: 15-Azido-4,7,10,13-tetraoxapentadecanoic acid, 3-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid, Polyethylene glycol
• Formula empirica (notazione di Hill): C₁₁H₂₁N₃O₆
• Numero CAS: 1257063-35-6
• Peso molecolare: 291.30
• Numero MDL: MFCD12406155
• Codice UNSPSC: 12352106
• ID PubChem: 329823931
• NACRES: NA.22

Proprietà

• Saggio: >90%
• Stato: solid or viscous liquid
• Impiego in reazioni chimiche: reaction type: click chemistry; reagent type: cross-linking reagent; reaction type: click chemistry
• Gruppo funzionale: azide; carboxylic acid
• Architettura del polimero: shape: linear; functionality: heterobifunctional
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C
• Stringa SMILE: OC(CCOCCOCCOCCOCCN=[N+]=[N-])=O
• InChI: 1S/C11H21N3O6/c12-14-13-2-4-18-6-8-20-10-9-19-7-5-17-3-1-11(15)16/h1-10H2,(H,15,16); BODPHGOBXPGJKO-UHFFFAOYSA-N

Descrizione

Caratteristiche e vantaggi

The azido-dPEG^®₄ contains an azide function on one end of a single molecular weight dPEG^® spacer (17.7 Å) and a reactive group on the other end of the spacer. The dPEG^® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The acid function may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

Note legali

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable