G11950

Guanine

98%

• Sinonimo/i: 2-Amino-1,7-dihydro-6H-purin-6-one, 2-Amino-6-hydroxypurine, 2-Aminohypoxanthine
• Formula empirica (notazione di Hill): C₅H₅N₅O
• Numero CAS: 73-40-5
• Peso molecolare: 151.13
• Beilstein: 9680
• Numero CE: 200-799-8
• Numero MDL: MFCD00071533
• Codice UNSPSC: 12352005
• ID PubChem: 24895050
• NACRES: NA.22

Proprietà

• Livello qualitativo: 200
• Saggio: 98%
• Punto di fusione: >300 °C (lit.)
• Solubilità: hydrochloric acid: soluble 5 M, clear to slightly hazy, colorless to faintly yellow-green
• Stringa SMILE: NC1=Nc2[nH]cnc2C(=O)N1
• InChI: 1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11); UYTPUPDQBNUYGX-UHFFFAOYSA-N

Descrizione

Descrizione generale

Adenine, cytosine, thymine and guanine are the four main nucleobases found in nucleic acids DNA and RNA. Guanine is a purine derivative. It is reported to assemble into square-planar groups that resemble macrocycles, in which the bases interact via hydrogen bonds. In DNA and RNA, stretches of guanine bases are reported to form stable four stranded helices in the presence of sodium or potassium ions. The electrochemical oxidation of guanine has been studied in aqueous media at various carbon electrodes. It reacts with peroxynitrite under physiological conditions to afford 8-nitroguanine.

Applicazioni

Guanine is suitable reagent used to investigate the mechanism of electrochemical oxidation of guanine and adenine using a glassy carbon microelectrode and cyclic and differential pulse voltammetry. It may be used in the preparation of mixed-sequence peptide nucleic acid (PNA) monomers.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H315,H319,H335
• Consigli di prudenza: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classi di pericolo: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves