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B103608

Sigma-Aldrich

γ-Butyrolactone

ReagentPlus®, ≥99%

Sinonimo/i:

gamma-Butyrolactone, γ-Hydroxybutyric acid lactone, 4-Hydroxybutyric acid lactone, GBL

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About This Item

Formula empirica (notazione di Hill):
C4H6O2
Numero CAS:
96-48-0
Peso molecolare:
86.09
Beilstein:
105248
Numero CE:
202-509-5
Numero MDL:
MFCD00005386
Codice UNSPSC:
12352100
ID PubChem:
24891553
NACRES:
NA.22

Densità del vapore

3 (vs air)

Tensione di vapore

1.5 mmHg ( 20 °C)

Nome Commerciale

ReagentPlus®

Saggio

≥99%

Forma fisica

liquid

Temp. autoaccensione

851 °F

Limite di esplosione

16 %

Indice di rifrazione

n20/D 1.436 (lit.)

P. eboll.

204-205 °C (lit.)

Punto di fusione

−45 °C (lit.)

Densità

1.12 g/mL at 25 °C (lit.)

Stringa SMILE

O=C1CCCO1

InChI

1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2
YEJRWHAVMIAJKC-UHFFFAOYSA-N

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Categorie correlate

Applicazioni

For the introduction of 3-carboxypropyl side chain. Used as a component of electrolyte solutions in batteries and capacitors.

Azioni biochim/fisiol

Precursor of γ-hydroxybutyric acid (GHB). It blocks dopamine release by blocking impulse flow in dopaminergic neurons. Pretreatment with γ-butyrolactone allows detection of autoreceptor-induced dopamine release.

Note legali

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Pittogrammi

CorrosionExclamation mark
GHS05,GHS07

Avvertenze

Danger

Indicazioni di pericolo

H302,H318,H336

Classi di pericolo

Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3

Organi bersaglio

Central nervous system

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

208.4 °F - closed cup

Punto d’infiammabilità (°C)

98 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificati d'analisi (COA)

Lot/Batch Number
STBK8622
STBK6651
STBK6169
STBK2578
STBK0998

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1,4-Butanediol ReagentPlus®, 99%

Sigma-Aldrich

493732

1,4-Butanediol

GHB-d6 sodium salt solution 1.0 mg/mL in methanol (as salt), ampule of 1 mL, certified reference material, Cerilliant®

Supelco

G-006

GHB-d6 sodium salt solution

Journal of Power Sources, 43, 195-195 (1993)
S Ohkawa et al.
Journal of medicinal chemistry, 34(1), 267-276 (1991-01-01)
A novel series of (3-pyridylmethyl)benzoquinone derivatives was molecular designed and synthesized for the dual purpose of inhibiting thromboxane A2 and leukotriene biosynthesis enzymes and scavenging active oxygen species (AOS). They were evaluated for inhibition of TXA2 synthase, inhibition of 5-lipoxygenase
Monica Blichowski et al.
Epilepsia, 56(7), 1081-1087 (2015-06-03)
Infantile spasms (or IS) is a catastrophic childhood epilepsy that is particularly prevalent in children with Down syndrome. Previously, we have shown that the Ts65Dn (Ts) mouse model of Down syndrome is a useful substrate upon which to develop an
Jagan N Thupari et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(14), 9498-9502 (2002-06-13)
C75, a known inhibitor of fatty acid synthase is postulated to cause significant weight loss through decreased hypothalamic neuropeptide Y (NPY) production. Peripherally, C75, an alpha-methylene-gamma-butyrolactone, reduces adipose tissue and fatty liver, despite high levels of malonyl-CoA. To investigate this
Tezcan Guney et al.
Organic letters, 15(3), 613-615 (2013-01-18)
The total synthesis of paracaseolide A, a valuable cell-cycle progression inhibitor, was accomplished in 8 steps from known compounds, with 6.6% overall yield. The synthetic strategy creates strong potential for diversification.
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Protocolli

GC Analysis of Volatiles in Roasted Coffee Beans on Omegawax® after SPME using a 50/30 µm DVB/Carboxen/PDMS Fiber

-Cymene; 2,5-Dimethylpyrrole; Acetoin, ≥96%, FCC, FG; 2,5-Dimethylpyrazine; 2,6-Dimethylpyrazine; 2-Ethylpyrazine, ≥98%, FG; 2,3-Dimethylpyrazine; 4-Heptanone; 3-Ethylpyridine; 2,3,5-Trimethylpyrazine; Furfural; Pyrrole; Furfuryl acetate; Linalool; Linalyl acetate; 5-Methylfurfural; γ-Butyrolactone; 2-Acetyl-1-methylpyrrole; Furfuryl alcohol; 2-Acetylpyrrole; Pyrrole-2-carboxaldehyde

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