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A7256

Sigma-Aldrich

DL-Norepinephrine hydrochloride

crystalline, ≥97% (TLC)

Sinonimo/i:

(±)-1-(3,4-Dihydroxyphenyl)-2-aminoethanol hydrochloride, (±)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol hydrochloride, DL-Arterenol hydrochloride, DL-Noradrenaline hydrochloride

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About This Item

Formula condensata:
(HO)2C6H3CH(OH)CH2NH2 · HCl
Numero CAS:
55-27-6
Peso molecolare:
205.64
Beilstein:
3707003
Numero CE:
200-229-8
Numero MDL:
MFCD00012880
Codice UNSPSC:
12352100
ID PubChem:
57653879
NACRES:
NA.22

Saggio

≥97% (TLC)

Stato

crystalline

Colore

off-white to tan

Solubilità

water: soluble 50 mg/mL, clear to slightly hazy, faintly yellow to brownish-yellow

Temperatura di conservazione

−20°C

Stringa SMILE

NCC(C1=CC(O)=C(C=C1)O)O.Cl

InChI

1S/C8H11NO3.ClH/c9-4-8(12)5-1-2-6(10)7(11)3-5;/h1-3,8,10-12H,4,9H2;1H
FQTFHMSZCSUVEU-UHFFFAOYSA-N

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Descrizione generale

DL-Norepinephrine hydrochloride is an adrenergic drug.

Applicazioni

DL-Norepinephrine hydrochloride is suitable adrenergic drug used in the following studies:
  • To investigate the effects of adrenergic drugs on lantern of larval fly.
  • To evaluate the ability of α-adrenergic stimulation in the presence of elevated calcium levels to induce delayed after depolarizations and triggered activity in Purkinje fibers isolated from cat hearts.
  • Simultaneous reduction and surface functionalization of graphene oxide by a one-step poly(norepinephrine) functionalization.

Altre note

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Pittogrammi

Skull and crossbones
GHS06

Avvertenze

Danger

Indicazioni di pericolo

H301

Classi di pericolo

Acute Tox. 3 Oral

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number
MKCQ5284
MKCP5464
MKCL5708
MKCG2176
MKCC1425

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N1100000

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(±)-Norepinephrine-D6 hydrochloride solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

Supelco

N-069

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Serotonina powder

Sigma-Aldrich

H9523

Serotonina

Catecholamine Mix 1 (Epinephrines) solution 1.0 mg/mL each component in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

Supelco

C-109

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Cirazoline hydrochloride solid

Sigma-Aldrich

C223

Cirazoline hydrochloride

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Supelco

E-077

(±)-Epinephrine-D6 solution

S Kimura et al.
Circulation, 70(6), 1074-1082 (1984-12-01)
We studied the ability of alpha-adrenergic stimulation to induce delayed afterdepolarizations and triggered activity in Purkinje fibers from cat hearts in the presence of an elevated Ca++ concentration. Delayed afterdepolarizations could not be induced at drive cycle lengths of 200
Effect of adrenergic drugs on the lantern of the larval Photuris firefly.
A D Carlson
The Journal of experimental biology, 48(2), 381-387 (1968-04-01)
Simultaneous Reduction and Surface Functionalization of Graphene Oxide by Mussel-Inspired Chemistry.
Kang SM, et al.
Advances in Functional Materials, 21(1), 108-112 (2011)
Yuki Komoto et al.
Scientific reports, 10(1), 11244-11244 (2020-07-11)
The analysis of neurotransmitters in the brain helps to understand brain functions and diagnose Parkinson's disease. Pharmacological inhibition experiments, electrophysiological measurement of action potentials, and mass analysers have been applied for this purpose; however, these techniques do not allow direct
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Journal of medicinal chemistry, 64(8), 4553-4566 (2021-04-13)
Finasteride, a 5-alpha reductase (5α-R) inhibitor, is a widely used drug for treating androgen-dependent conditions. However, its use is associated with sexual, psychological, and physical complaints, suggesting that other mechanisms, in addition to 5α-R inhibition, may be involved. Here, a
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