901332

Polyester bis-MPA dendron 8 NHBoc, 1 azide (core)

generation 3

• Sinonimo/i: Bis-MPA dendron, PFd-G3-Azide-NH-BOC
• Formula empirica (notazione di Hill): C₁₀₅H₁₇₃N₁₁O₄₆
• Peso molecolare: 2325.54
• Codice UNSPSC: 12352125
• NACRES: NA.23

Proprietà

• Descrizione: 8 NHBoc, 1 azide (core)
• Livello qualitativo: 100
• Stato: solid
• PM: generation 3
• N° gruppi superficiali: 8
• Colore: white to off-white
• Gruppo funzionale: azide (core)
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

• Polymer architecture: Dendron
• End Group Functionality: Boc-protected amine
• Boc : tert-Butyloxycarbonyl
• Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid.

Applicazioni

Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research applications. These materials have been used in many applications such as signal amplification in bioassays and in drug delivery applications. After Boc deprotection, amine-functionalized dendrons can be readily used in EDC or DCC coupling reactions with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical applications. Additionally, the azide-core can be readily conjugated using either copper(I)-catalysed alkyne-azide cycloaddition (CuAAC) or strain-promoted alkyne-azide cycloaddition (SPAAC).

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable