900258

Isopropoxy(phenyl)silane

• Sinonimo/i: RubenSilane
• Formula empirica (notazione di Hill): C₉H₁₄OSi
• Numero CAS: 910037-63-7
• Peso molecolare: 166.29
• Numero MDL: MFCD31707672
• Codice UNSPSC: 12352005
• NACRES: NA.22

Proprietà

• Stato: liquid
• Livello qualitativo: 100
• Impiego in reazioni chimiche: reagent type: reductant; reaction type: Reductions
• Indice di rifrazione: n/D 1.4799
• Densità: 0.926 g/mL
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: [SiH2](OC(C)C)c1ccccc1
• InChI: 1S/C9H14OSi/c1-8(2)10-11-9-6-4-3-5-7-9/h3-8H,11H2,1-2H3; XYMAHMLQCLMTDN-UHFFFAOYSA-N

Descrizione

Descrizione generale

Isopropoxy(phenyl)silane is used as a stoichiometric reductant that allows for a significant decrease in catalyst loading, lower reaction temperatures, a wide range of functional group tolerance, and more diverse solvents in metal-catalyzed Mukaiyama hydrofunctionalizations.

Applicazioni

Isopropoxy(phenyl)silane can be used as a hydride source for alkene hydrofunctionalization reactions in the presence of metal catalysts, particularly under aprotic, nonalcoholic conditions. This reagent is considered as one of the most efficient stoichiometric reductants than phenylsilane because of its ability to exclude alcohol solvent from a series of catalytic reactions. When utilized, it allows the researcher to significantly decrease catalyst loadings, lower reaction temperatures, and employ more diverse solvents in iron- and manganese-catalyzed Mukaiyama hydrofunctionalizations.
It can be used as a reagent in:

• The hydrogenation of olefins
• Branch-selective olefin cross-coupling reactions
• Markovnikov alkene hydration/amination reactions

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3