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Key Documents

572667

Sigma-Aldrich

Baicalin

95%

Sinonimo/i:

5,6-Dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid, Baicalein 7-O-β-D-glucuronide

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About This Item

Formula empirica (notazione di Hill):
C21H18O11
Numero CAS:
Peso molecolare:
446.36
Numero MDL:
Codice UNSPSC:
12352201
ID PubChem:
NACRES:
NA.22

Livello qualitativo

Saggio

95%

Forma fisica

solid

Attività ottica

[α]20/D −85°, c = 1 in DMSO

Punto di fusione

202-205 °C (dec.) (lit.)

Stringa SMILE

O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2cc3OC(=CC(=O)c3c(O)c2O)c4ccccc4

InChI

1S/C21H18O11/c22-9-6-10(8-4-2-1-3-5-8)30-11-7-12(14(23)15(24)13(9)11)31-21-18(27)16(25)17(26)19(32-21)20(28)29/h1-7,16-19,21,23-27H,(H,28,29)/t16-,17-,18+,19-,21+/m0/s1
IKIIZLYTISPENI-ZFORQUDYSA-N

Informazioni sul gene

mouse ... Hexa(15211)

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Descrizione generale

Baicalin is a key flavonoid found in the roots of Scutellaria baicalensis. It is known to have different biological activities, such as anti-oxidative, anti-inflammatory, antitumor and anti-apoptotic activities.

Applicazioni

Baicalin has been used in a study to examine its neuroprotective effect in chronically stressed rats.2

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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Certificati d'analisi (COA)

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Paeoniflorin ≥98% (HPLC)

Sigma-Aldrich

P0038

Paeoniflorin

Baicalein A cell-permeable flavone that inhibits the activity of 12-lipoxygenase (IC₅₀= 120 nM) and reverse transcriptase.

Sigma-Aldrich

196322

Baicalein

Schizandrin ≥98% (HPLC)

Sigma-Aldrich

SML0054

Schizandrin

Gomisin A

Sigma-Aldrich

SML1251

Gomisin A

Leonurine ≥98% (HPLC)

Sigma-Aldrich

SML0670

Leonurine

Baicalin Attenuates Hypoxia-Induced Pulmonary Arterial Hypertension to Improve Hypoxic Cor Pulmonale by Reducing the Activity of the p38 MAPK Signaling Pathway and MMP-9.
Yan S, et al.
Evidence-Based Complementary and Alternative Medicine : ECAM, 2016 (2016)
Baicalin influences the dendritic morphology of newborn neurons in the hippocampus of chronically stressed rats.
Jiang X, et al.
Neural Regeneration Research, 8(6), 496-496 (2013)
Peng-Fei Yue et al.
International journal of pharmaceutics, 443(1-2), 279-287 (2013-01-08)
Baicalin nanosuspensions, stabilized with 10% TPGS (relative to the weight of baicalin), were transformed into nanosuspensions powders by solidification process. Solidification methods for this transformation included freeze-drying, spray drying or vacuum drying. High pressure homogenization was applied for production of
Peng-Wei Zhuang et al.
CNS neuroscience & therapeutics, 19(3), 154-162 (2013-01-11)
Recent studies revealed that baicalin, a flavonoid compound derived from the root of Scutellaria baicalensis Georgi, could promote neuron differentiation of NSPCs after commencing the differentiation process in vitro. However, this may not be the most efficacious strategy to determinate
Qi Wang et al.
Molecular and cellular biochemistry, 463(1-2), 91-100 (2019-10-14)
Baicalin (BAI), a sort of flavonoid monomer, acquires from Scutellaria baicalensis Georgi, which was forcefully reported in diversified ailments due to the pleiotropic properties. But, the functions of BAI in osteoblast differentiation have not been addressed. The intentions of this study

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