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P0038

Sigma-Aldrich

Paeoniflorin

≥98% (HPLC)

Sinonimo/i:

NSC 178886, Peoniflorin

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About This Item

Formula empirica (notazione di Hill):
C23H28O11
Numero CAS:
Peso molecolare:
480.46
Numero CE:
Numero MDL:
Codice UNSPSC:
12352201
ID PubChem:
NACRES:
NA.25

Origine biologica

plant (Paeonia Albiflora)

Saggio

≥98% (HPLC)

Forma fisica

powder

tecniche

HPLC: suitable

Impurezze

<3.0% water (Karl Fischer)

Colore

white

Solubilità

water: insoluble

Temperatura di conservazione

2-8°C

Stringa SMILE

C[C@@]12C[C@@]3(O)O[C@@H](O1)[C@]5(COC(=O)c4ccccc4)[C@H]3C[C@]25O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O

InChI

1S/C23H28O11/c1-20-9-22(29)13-7-23(20,32-18-16(27)15(26)14(25)12(8-24)31-18)21(13,19(33-20)34-22)10-30-17(28)11-5-3-2-4-6-11/h2-6,12-16,18-19,24-27,29H,7-10H2,1H3/t12-,13-,14-,15+,16-,18+,19-,20+,21+,22-,23+/m1/s1
YKRGDOXKVOZESV-WRJNSLSBSA-N

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Descrizione generale

Paeoniflorin has been demonstrated to exert anti-inflammatory and immunomodulatory effects.

Applicazioni

Paeoniflorin was used to treat rats with collagen-induced arthritis in a study to assess the pro-apoptotic effect of Epigallo-catechin-3-gallate on B lymphocytes.

Azioni biochim/fisiol

Herbal constituent of peony root. It is used in Chinese traditional medicine for its spasmolytic and pain-relieving properties. Exhibits anticoagulant, neuromuscular blocking, cognition-enhancing, immunoregulating, and antihyperglycemic effects.

Altre note

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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Wei Zhang et al.
International immunopharmacology, 14(1), 27-31 (2012-06-19)
Paeonia lactiflora Pallas, also named Chinese Paeony, is a Chinese herb. A decoction of its root has been used to treat painful or inflammatory disorders in traditional Chinese medicine. A water/ethanol extract of Radix Paeoniae is known as total glycosides
Dandan Liu et al.
European journal of pharmacology, 690(1-3), 214-225 (2012-07-05)
To investigate the role of PI3K/Akt/mTOR signaling mediated by B cell-activating factor belonging to the TNF family (BAFF) involved in anti-apoptosis of B lymphocytes in rats with collagen-induced arthritis (CIA) and the regulation of epigallo-catechin-3-gallate (EGCG). Sprague-Dawley rats were immunized
Jie Wu et al.
Molecules (Basel, Switzerland), 17(8), 8938-8954 (2012-07-28)
Detection of sulfur-fumigated Paeoniae Alba Radix (PAR) in different complex preparations is challenging due to the relatively lower content of PAR and interference from more complicated components in complex preparations with different multiple constituent herbs. In this study, a high
Hsiang-Ru Lin
Journal of Asian natural products research, 15(1), 35-45 (2013-01-04)
Paeoniflorin is one of the active ingredients of Paeonia lactiflora Pall., a novel traditional herbal medicine exerting pharmacological effects including antihyperlipidemic, neuroprotective, and anti-hepatofibrosis effects. Liver X receptor (LXR) acts as a ligand-activated transcription factor to exhibit antihyperlipidemic and neuroprotective
Naglaa Fathy Abd El-Aal et al.
Experimental parasitology, 197, 85-92 (2018-11-12)
Chronic hepatic schistosomiasis causes portal hypertension, fibrosis and lethal hepatosplenic complications. Previous studies focused mainly on schistosomicidal drugs and neglected the therapeutic approaches against the vascular complications after portal hypertension. Investigating a novel anti-angiogenic therapy is an urgent. The current

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