468495

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate

97%

• Sinonimo/i: DiI
• Formula empirica (notazione di Hill): C₅₉H₉₇ClN₂O₄
• Numero CAS: 41085-99-8
• Peso molecolare: 933.87
• Beilstein: 8251870
• Numero MDL: MFCD00142354
• Codice UNSPSC: 12171500
• ID PubChem: 24870519
• NACRES: NA.47

Proprietà

• Livello qualitativo: 100
• Saggio: 97%
• Forma fisica: crystalline
• Composizione: Carbon: 73.2-78.5%; ; Nitrogen: 2.7-3.3%
• Colore: dark purple
• Punto di fusione: 68 °C (dec.) (lit.)
• λmax: 549 nm
• ε (coefficiente d’estinzione): ≥10000 at 276-282 nm in methanol at 0.01 g/L; ≥130000 at 546-552 nm in methanol at 0.01 g/L; ≥70000 at 514-520 nm in methanol at 0.01 g/L
• applicazioni: diagnostic assay manufacturing; hematology; histology
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: [O-]Cl(=O)(=O)=O.CCCCCCCCCCCCCCCCCCN1c2ccccc2C(C)(C)/C1=C\C=C\C3=[N+](CCCCCCCCCCCCCCCCCC)c4ccccc4C3(C)C
• InChI: 1S/C59H97N2.ClHO4/c1-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-41-50-60-54-46-39-37-44-52(54)58(3,4)56(60)48-43-49-57-59(5,6)53-45-38-40-47-55(53)61(57)51-42-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-2;2-1(3,4)5/h37-40,43-49H,7-36,41-42,50-51H2,1-6H3;(H,2,3,4,5)/q+1;/p-1; JVXZRNYCRFIEGV-UHFFFAOYSA-M

Descrizione

Descrizione generale

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate is also called as Dil. It can be used to study HCV (Hepatitis C virus) cell interactions in the HCV entry process. It is used to label oxidized LDL (low-density lipoprotein) to quantify the uptake of DiI-oxLDL in human endothelial cells.

Applicazioni

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate has been used in cytoskeletal staining, nuclear staining, retrograde labeling, counting of motor neurons and labelling of the retinal ganglion cell axons.

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate has been used in fluorescent labelling of mesenchymal stem cells (MSCs) and cerebral cortex. It has also been used in electromyogram (EMG) to determine awake and anesthetized states in mice.

Azioni biochim/fisiol

Lipophilic carbocyanine dye used primarily for optical recordings of membrane voltage and for studies of membrane fluidity. Retrograde stain for neurons; provides intense, long-lasting staining of live neurons in vivo and in vitro.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)