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409472

Sigma-Aldrich

N-[3-(Dimethylamino)propyl]methacrylamide

99%, contains MEHQ as inhibitor

Sinonimo/i:

N ,N -Dimethylaminopropyl methacrylamide, N -[3-(N ,N -Dimethylamino)propyl]methacrylamide

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About This Item

Formula condensata:
H2C=C(CH3)CONH(CH2)3N(CH3)2
Numero CAS:
Peso molecolare:
170.25
Numero CE:
Numero MDL:
Codice UNSPSC:
12162002
ID PubChem:
NACRES:
NA.23

Livello qualitativo

Descrizione

contains: ~650ppm MEHQ as inhibitor

Saggio

99%

Forma fisica

viscous liquid

Indice di rifrazione

n20/D 1.479 (lit.)

P. eboll.

134 °C/2 mmHg (lit.)

Densità

0.94 g/mL at 25 °C (lit.)

Stringa SMILE

CN(C)CCCNC(=O)C(C)=C

InChI

1S/C9H18N2O/c1-8(2)9(12)10-6-5-7-11(3)4/h1,5-7H2,2-4H3,(H,10,12)
GDFCSMCGLZFNFY-UHFFFAOYSA-N

Descrizione generale

N-[3-(Dimethylamino)propyl]Methacrylamide (DMAPMA) is a water-soluble methacrylamide monomer. It is highly reactive and can undergo radical polymerization and cross-linking reactions. The presence of methylamino group (-N(CH3)2) provides pH responsiveness and hydrophilicity to the resulting polymers. This versatile monomer can be used in drug delivery systems, gene delivery, responsive materials, biocompatible coatings, adhesives, and biomedical engineering.

Applicazioni


  • Glucose-containing diblock polycations exhibit molecular weight, charge, and cell-type dependence for pDNA delivery.: This study investigates the use of glucose-containing diblock polycations, including N-[3-(Dimethylamino)propyl]methacrylamide, in pDNA delivery systems. The research demonstrates that the efficiency of pDNA delivery is influenced by the molecular weight and charge of the polycations, as well as the type of cell used. This highlights the potential for tailored gene delivery applications in different cell types, emphasizing the role of N-[3-(Dimethylamino)propyl]methacrylamide in creating biocompatible and effective delivery vectors (Wu et al., 2014).

N-[3-(Dimethylamino)propyl]Methacrylamide can be used:



  • As a monomer to synthesize self-healing pH-responsive P(DMAPMA-stat-DAA) hydrogels for drug delivery applications.
  • As a cationic monomer to develop gene delivery vector due to its ability to complex with nucleic acids and facilitate their intracellular delivery.
  • To fabricate iron oxide nanoparticle formulations for 3D printing. These iron inks are utilized for printing magnetic devices, MRI contrast agents for bioimaging and targeted drug delivery systems.
  • To prepare a non-toxic synthetic flocculant for harvesting microalgae.

Pittogrammi

CorrosionExclamation mark

Avvertenze

Danger

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

264.2 °F - closed cup

Punto d’infiammabilità (°C)

129 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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John E Blume et al.
Nature communications, 11(1), 3662-3662 (2020-07-24)
Large-scale, unbiased proteomics studies are constrained by the complexity of the plasma proteome. Here we report a highly parallel protein quantitation platform integrating nanoparticle (NP) protein coronas with liquid chromatography-mass spectrometry for efficient proteomic profiling. A protein corona is a
Merve Yaşar et al.
Journal of biomaterials science. Polymer edition, 31(16), 2044-2059 (2020-07-10)
The fabrication of molecularly imprinted nanoparticles (MIP-NPs) specific for myoglobin by using thiol-ene photopolymerization in miniemulsion was described. Allyl derivatives of phenylalanine as a functional monomer was synthesized and copolymerized with acrylic monomers via miniemulsion polymerization to produce NIP-NPs with

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