730971
2-(Diisopropylamino)ethyl methacrylate
97%, contains ~100 ppm monomethyl ether hydroquinone as inhibitor
Sinonimo/i:
DPA, DPAEMA
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About This Item
Formula empirica (notazione di Hill):
C12H23NO2
Numero CAS:
Peso molecolare:
213.32
Numero CE:
Numero MDL:
Codice UNSPSC:
12162002
ID PubChem:
NACRES:
NA.23
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Livello qualitativo
Saggio
97%
Stato
liquid
contiene
~100 ppm monomethyl ether hydroquinone as inhibitor
Indice di rifrazione
n20/D 1.145
Densità
0.900 g/mL at 25 °C
Temperatura di conservazione
2-8°C
Stringa SMILE
CC(C)N(CCOC(=O)C(C)=C)C(C)C
InChI
1S/C12H23NO2/c1-9(2)12(14)15-8-7-13(10(3)4)11(5)6/h10-11H,1,7-8H2,2-6H3
SVYHMICYJHWXIN-UHFFFAOYSA-N
Descrizione generale
2-(Diisopropylamino)ethyl methacrylate (DPA) is a methacrylate class of monomer used to prepare various DPA-derived polymers, which includes poly(2-(diisopropylamino)ethyl methacrylate) (PDPA). PDPA is a water-soluble polymer, which exhibits sensitivity to changes in pH and temperature. At pH levels below its pKa value of approximately 6.5, PDPA undergoes a transition from hydrophobic to hydrophilic behavior. This transition is attributed to the protonation of its amino groups. These unique properties of PDPA polymers consequently make them very useful in various applications such as drug delivery, gene delivery, sensors, surfaces, membranes, and chromatography.
Applicazioni
2-(Diisopropylamino)ethyl methacrylate can be used:
- As a monomer in the synthesis of multi-responsive hyperbranched copolymers by combining poly(oligo(ethylene glycol)methyl methacrylate) (P(OEGMA)) and 2-(diisopropylamino)ethyl methacrylate (PDIPAEMA) using RAFT polymerization. These polymers find application in drug delivery, gene delivery and tissue engineering.
- A monomers in the synthesis of block copolymer poly(ethyleneglycol)-b-poly(2-(diisopropylamino)ethyl methacrylate) (PEG-b-PDPAEMA). These pH-responsive micelles can be used for enhanced intracellular drug delivery. The DPA monomer contributes to the pH-responsive nature of the copolymers.
Avvertenze
Danger
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Organi bersaglio
Respiratory system
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
210.0 °F
Punto d’infiammabilità (°C)
98.9 °C
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