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380563

Sigma-Aldrich

2-Amino-5-methylthiazole

98%

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About This Item

Formula empirica (notazione di Hill):
C4H6N2S
Numero CAS:
7305-71-7
Peso molecolare:
114.17
Beilstein:
109603
Numero MDL:
MFCD00078317
Codice UNSPSC:
12352100
ID PubChem:
24863751
NACRES:
NA.22

Saggio

98%

Forma fisica

powder

Punto di fusione

93-98 °C (lit.)

Stringa SMILE

Cc1cnc(N)s1

InChI

1S/C4H6N2S/c1-3-2-6-4(5)7-3/h2H,1H3,(H2,5,6)
GUABFMPMKJGSBQ-UHFFFAOYSA-N

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Descrizione generale

2-Amino-5-methylthiazole is a heterocyclic building block. It is one of the major alkaline metabolite of tenoxicam (TX) and meloxicam (MX).

Applicazioni

2-Amino-5-methylthiazole may be used in the preparation of acrylamide monomer, 5-methyl-2-thiozyl methacrylamide (MTMAAm).
2-Amino-5-methylthiazole may be used in the preparation of mixed-ligand dien-Cu(II) complexes (dien=diethylenetriamine). It may be used in the preparation of a new series of Schiff mono/dibase coordination compounds, having potential anticancer and antibacterial activities.

Avvertenze

Warning

Indicazioni di pericolo

H302,H373,H410

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Slide 1 of 5

1 of 5

vibrant-m

Y0001039

Meloxicam impurity D

USP

USP

1379434

Meloxicam Related Compound C

Meloxicam Related Compound A United States Pharmacopeia (USP) Reference Standard

USP

1379412

Meloxicam Related Compound A

vibrant-m

Y0001037

Meloxicam impurity C

2-(Aminomethyl)thiazole 97%

Sigma-Aldrich

721522

2-(Aminomethyl)thiazole

Synthesis and characterization of new chelating resin: adsorption study of copper (II) and chromium (III) ions.
Sacmaci S, et al.
Journal of Macromolecular Science, Part A: Pure and Applied Chemistry, 47(6), 552-557 (2010)
C A Bolos et al.
Journal of inorganic biochemistry, 88(1), 25-36 (2001-12-26)
The reaction of [Cu(dien)NO(3)]NO(3) with 2-amino-5-methylthiazole (2A5MT), 2-amino-2-thiazoline (2A-2Tzn), imidazole (im), N,N'-thiocarbonyldiimidazole (Tcdim), 2-aminothiazole (2AT) and 2-ethylimidazole (2Etim), gave a new series of mixed-ligand compounds of the general formula [Cu(dien)(B)NO(3))]NO(3); (dien, diethylenetriamine; B, 2A5MT, 2A-2Tzn, im, Tcdim, 2AT and 2Etim).
A Th Chaviara et al.
Journal of inorganic biochemistry, 98(8), 1271-1283 (2004-07-24)
A new series of coordination compounds of the starting materials [Cu(dienX(2)Y(2))] and their adducts [Cu(dienXXY(2))(2a-5mt)] (where dien=diethylenetriamine, dienXX=Schiff bases of diethylenetriamine with 2-furaldehyde or 2-thiophene-carboxaldehyde, X=O, S, Y=Cl, Br, NO(3) and 2a-5mt=2-amino-5-methylthiazole) were synthesized by stepwise reactions and their structures
E Pontiki et al.
Journal of enzyme inhibition and medicinal chemistry, 23(6), 1011-1017 (2008-11-14)
Highly reactive radicals are implicated in many pathological conditions. The quest for radical scavengers or antioxidants, spans the previous decades. A new series of complexes of the type [Cu (dien) (2a-2tzn) Y(2)] and [Cu (dienXXY(2)) (2a-5mt)] and of the type
Ratio derivative spectrophotometric method for the determination of some oxicams in presence of their alkaline degradation products.
Taha EA, et al.
Scientia Pharmaceutica, 71(4), 303-320 (2003)
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