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Documenti fondamentali

318183

Sigma-Aldrich

Methyl sulfate sodium salt

Sinonimo/i:

Monomethyl ester sulfuric acid sodium salt, Sodium methyl sulfate

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About This Item

Formula condensata:
CH3OSO3Na
Numero CAS:
Peso molecolare:
134.09
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

Stato

powder

Livello qualitativo

Impurezze

<3% methanol
<5% water

Punto di fusione

210 °C (lit.)

Stringa SMILE

[Na+].COS([O-])(=O)=O

InChI

1S/CH4O4S.Na/c1-5-6(2,3)4;/h1H3,(H,2,3,4);/q;+1/p-1
DZXBHDRHRFLQCJ-UHFFFAOYSA-M

Applicazioni

Methyl sulfate sodium salt can be used to synthesize:
  • Methylsulfate anion based 1,3,4-trialkyl-1,2,3-triazolium ionic liquids for use in Morita–Baylis–Hillman reaction.
  • Anisole by reacting with phenol.
  • Hydroxyanilino quinolines for use as RET kinase inhibitors.

Reactant or reagent involved in:
  • Studying lamellar structure formation in hybrid nanomaterials created by miniemulsion
  • EPR studies of radical ions radiolytically generated from ionic liquids, used as a reference
  • Micellular studies specifically the rate-retarding effects on hydrolysis of substituted 1-benzoyl-1,2,4-triazoles and self-assembly / microstructure of mixed micelles

Pittogrammi

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Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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Synthesis of anisole from phenol and sodium methyl sulfate, a byproduct from synthesis of medicine intermediates
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M A Sallam et al.
Carbohydrate research, 330(1), 53-63 (2001-02-24)
Dehydration of 4-(D-galacto-pentitol-1-yl)-2-phenyl-2H-1,2,3-triazole with 20% methanolic sulfuric acid afforded the anomeric pairs of nucleosides, 4-(alpha-D-lyxopyranosyl)-2-phenyl-2H-1,2,3-triazole (major component) and its beta-anomer, as well as 4-(alpha-D-lyxofuranosyl)-2H-1,2,3-triazole and its beta-anomer. The four anomeric C-nucleosides were separated by chromatography, and their structure and anomeric
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