275778
Imidazo[1,2-a]pyridine
99%
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About This Item
Formula empirica (notazione di Hill):
C7H6N2
Numero CAS:
Peso molecolare:
118.14
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22
Prodotti consigliati
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![Imidazo[1,2-a]pyrazine 97%](/deepweb/assets/sigmaaldrich/product/structures/370/804/1712d71f-52fb-4758-9a22-85b6c96cd4e8/640/1712d71f-52fb-4758-9a22-85b6c96cd4e8.png)
![Imidazo[1,2-a]pyrimidine AldrichCPR](/deepweb/assets/sigmaaldrich/product/structures/187/001/4862c14e-bec7-4475-85a5-f178e48ff60f/640/4862c14e-bec7-4475-85a5-f178e48ff60f.png)
Saggio
99%
Forma fisica
liquid
Indice di rifrazione
n20/D 1.626 (lit.)
P. eboll.
103 °C/1 mmHg (lit.)
Densità
1.165 g/mL at 25 °C (lit.)
Stringa SMILE
c1ccn2ccnc2c1
InChI
1S/C7H6N2/c1-2-5-9-6-4-8-7(9)3-1/h1-6H
UTCSSFWDNNEEBH-UHFFFAOYSA-N
Categorie correlate
Descrizione generale
In vivo anti-trypanosomal activity of imidazo[1,2-a]pyridiness in the STIB900 mouse model has been investigated.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Organi bersaglio
Respiratory system
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
235.4 °F - closed cup
Punto d’infiammabilità (°C)
113 °C - closed cup
Dispositivi di protezione individuale
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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I clienti hanno visto anche
Suren Husinec et al.
Organic letters, 13(9), 2286-2289 (2011-03-31)
A base promoted cyclization of the protected N-propargylaminopyridines was shown to be an efficient method for the preparation of imidazo[1,2-a]pyridine derivatives. The reactions were carried out with a small excess of base, at room temperature or slightly above producing the
Richard Ducray et al.
Bioorganic & medicinal chemistry letters, 21(16), 4698-4701 (2011-07-22)
We disclose a novel series of insulin-like growth factor-1 receptor kinase inhibitors based on the 3-(pyrimidin-4-yl)-imidazo[1,2-a]pyridine scaffold. The influence on the inhibitory activity of substitution on the imidazopyridine and at the C5 position of the pyrimidine is discussed. In the
Ebrahim Kianmehr et al.
Journal of combinatorial chemistry, 12(1), 41-44 (2009-11-13)
A one-pot, three-component reaction between pyridine, phenacyl bromide, and thiocyanate is described. The reaction afforded the corresponding special type of fully substituted imidazo[1,2-a]pyridine derivatives in good yields without using any catalyst or activation.
Richard Ducray et al.
Bioorganic & medicinal chemistry letters, 21(16), 4702-4704 (2011-07-19)
Following the discovery of imidazopyridine 1 as a potent IGF-1R tyrosine kinase inhibitor, the aniline part has been modified with the aim to optimize the properties of this series. The structure-activity relationships against IGF-1R kinase activity as well as inhibition
Hongpeng Sun et al.
The Journal of organic chemistry, 77(23), 10745-10751 (2012-11-22)
An efficient tandem route to the synthesis of 3H-1,2a(1),3-triazaacenaphthylene derivatives of the cyclazine family has been developed. Target compounds were obtained in moderate to good yields by a Yb(OTf)(3)/Ag(2)CO(3)-catalyzed, three-component domino reaction. This in turn will set the stage for
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