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Documenti fondamentali

247847

Sigma-Aldrich

2,6-Diaminopurine

98%

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About This Item

Formula empirica (notazione di Hill):
C5H6N6
Numero CAS:
Peso molecolare:
150.14
Numero CE:
Numero MDL:
Codice UNSPSC:
12162002
ID PubChem:
NACRES:
NA.23

Livello qualitativo

Saggio

98%

Punto di fusione

>300 °C (lit.)

Stringa SMILE

Nc1nc(N)c2nc[nH]c2n1

InChI

1S/C5H6N6/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H5,6,7,8,9,10,11)
MSSXOMSJDRHRMC-UHFFFAOYSA-N

Pittogrammi

Health hazardExclamation mark

Avvertenze

Warning

Classi di pericolo

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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Metotrexato ≥98% (HPLC), powder

Sigma-Aldrich

A6770

Metotrexato

Søren Lindemose et al.
Nucleic acids research, 36(14), 4797-4807 (2008-07-26)
The DNA interaction of the Escherichia coli cyclic AMP receptor protein (CRP) represents a typical example of a dual recognition mechanism exhibiting both direct and indirect readout. We have dissected the direct and indirect components of DNA recognition by CRP
V Krishnakumar et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 69(1), 8-17 (2007-05-01)
FT-IR and FT-Raman spectra of 2,6-diamino purine (DAP) and 6-methoxy purine (MP) have been recorded in the regions of 4000-400cm(-1) and 3500-100cm(-1), respectively. The spectra were interpreted with the aid of normal coordinate analysis following full structure optimizations and force
Miguel A Galindo et al.
Inorganic chemistry, 48(23), 11085-11091 (2009-10-28)
Alkyldiamine-tethered derivatives of 2,6-diaminopurine, ethylenediamine-N9-propyl-2,6-diaminopurine, L1, and ethylenediamine-N9-ethyl-2,6-diaminopurine, L2, react with Pd(II) to give N3-coordinated complexes. However, the exact nature of the resulting complex is dependent on the reaction conditions. With PdCl(2)(MeCN)(2) in MeCN/H(2)O the expected [PdCl(N3-2,6-DAP-alkyl-en)](+) complex, 1, is
Elizabeth Mburu et al.
The journal of physical chemistry. A, 112(48), 12485-12491 (2008-11-07)
Several excited singlet electronic states of purine nucleobases and related derivatives have been calculated using high-level multireference perturbation theory methods. Purine derivatives with one or two amino or carbonyl groups substituted at positions C(2) and/or C(6) of the purine ring
Kiyohiko Kawai et al.
Journal of the American Chemical Society, 132(2), 627-630 (2009-12-18)
A positive charge migrates along DNA mainly via a series of short-range charge transfer (CT) processes between G-C base pairs, which have relatively high HOMO levels. As such, the CT efficiency sharply decreases with the insertion of A-T base pairs

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