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Documenti fondamentali

185205

Sigma-Aldrich

Myristoyl chloride

97%

Sinonimo/i:

Tetradecanoyl chloride

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About This Item

Formula condensata:
CH3(CH2)12COCl
Numero CAS:
Peso molecolare:
246.82
Beilstein:
636924
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

Livello qualitativo

Saggio

97%

Stato

liquid

Indice di rifrazione

n20/D 1.449 (lit.)

P. ebollizione

250 °C/100 mmHg (lit.)

Punto di fusione

−1 °C (lit.)

Densità

0.908 g/mL at 25 °C (lit.)

Gruppo funzionale

acyl chloride

Stringa SMILE

CCCCCCCCCCCCCC(Cl)=O

InChI

1S/C14H27ClO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16/h2-13H2,1H3
LPWCRLGKYWVLHQ-UHFFFAOYSA-N

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Applicazioni

Myristoyl chloride was used in the synthesis of 6-azafulleroid-6-deoxy-2,3-di-O-myristoylcellulose. It was used in N-acylation of chitosan to introduce hydrophobicity for use as matrix for drug delivery. It was used in the synthesis of semi-crystalline dendritic poly(ether-amide) derivatives.

Pittogrammi

Corrosion

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

235.4 °F - closed cup

Punto d’infiammabilità (°C)

113 °C - closed cup

Dispositivi di protezione individuale

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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1 of 4

Synthesis and crystallinity of dendritic poly (ether-amide) derivatives.
Wei H, et al.
Eur. Polymer J., 38(9), 1899-1905 (2002)
Canh Le Tien et al.
Journal of controlled release : official journal of the Controlled Release Society, 93(1), 1-13 (2003-11-07)
N-acylation of chitosan with various fatty acid (C(6)-C(16)) chlorides increased its hydrophobic character and made important changes in its structural features. Unmodified chitosan exhibited a low degree of order (DO) and a weak tablet crushing strength. Chitosan acylated with a
Diego Romano Perinelli et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 109, 93-102 (2016-10-04)
Toxicity is one of the main concerns limiting the use of surfactants. Many efforts have been devoted to the development of new amphiphilic molecules characterized by a lower toxicological profile and environmental impact. N-acyl amino acids are a class of
Nobuhiko Ichihara et al.
Carbohydrate research, 346(15), 2515-2518 (2011-09-17)
6-Azafulleroid-6-deoxy-2,3-di-O-myristoylcellulose (3) was synthesized from 6-azido-6-deoxycellulose (1) by two reaction steps. The myristoylation of compound 1 with myristoyl chloride/pyridine proceeded smoothly to give 6-azido-6-deoxy-2,3-di-O-myristoylcellulose (2) in 97.0% yield. The reaction of compound 2 with fullerene (C(60)) was carried out by
Janclei P Coutinho et al.
Talanta, 134, 256-263 (2015-01-27)
In this work a multivariate statistical tool (Derringer and Suich optimization) was proposed for the separation of seventeen capsinoids (natural and synthetic) using the UHPLC-DAD chromatography. Capsinoids were analyzed at 280 nm. The variables optimized were the mobile phase (water

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