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14462

Sigma-Aldrich

(−)-α-Bisabolol

≥93% (GC)

Sinonimo/i:

(−)-6-Methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol, Levomenol

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About This Item

Formula empirica (notazione di Hill):
C15H26O
Numero CAS:
Peso molecolare:
222.37
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

Saggio

≥93% (GC)

Attività ottica

[α]/D -58±5°, neat

Indice di rifrazione

n20/D 1.496

Stringa SMILE

C\C(C)=C\CC[C@](C)(O)[C@H]1CCC(C)=CC1

InChI

1S/C15H26O/c1-12(2)6-5-11-15(4,16)14-9-7-13(3)8-10-14/h6-7,14,16H,5,8-11H2,1-4H3/t14-,15+/m1/s1
RGZSQWQPBWRIAQ-CABCVRRESA-N

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Descrizione generale

(-)-α-Bisabolol is the major constituent of essential oil from leaves of Hymenocrater yazdianus.

Applicazioni

(-)-α-Bisabolol was used to investigate the leishmanicidal and cytotoxic activity of essential oil of Vanillosmopsis arborea.

Azioni biochim/fisiol

α-Bisabolol is active against primary acute leukemia cells, including BCR-ABL(+) acute lymphoblastic leukemias. It is the inhibitor of voltage-dependent Ca(2+) channels in tracheal smooth muscle preparations of rat. It also inhibits human and rat glioma cell growth and survival. It is a potential new therapeutic agent against leishmaniasis.

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Aquatic Chronic 3

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

289.4 °F - closed cup

Punto d’infiammabilità (°C)

143 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Gloves


Certificati d'analisi (COA)

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Chamazulene phyproof® Reference Substance

PHL89174

Chamazulene

Ferutinin ≥98% (HPLC)

Sigma-Aldrich

SML1609

Ferutinin

Shiva Masoudi et al.
Natural product communications, 7(1), 117-120 (2012-03-21)
Water-distilled essential oils from leaves of Hymenocrater yazdianus Rech.f., flowers of Stachys obtusicrena Boiss., and stems and flowers of Nepeta asterotricha Rech.f., which are endemic to Iran, were analyzed by GC and GC/MS. Fifty-five components of the leaf oil of
Aracélio Viana Colares et al.
Evidence-based complementary and alternative medicine : eCAM, 2013, 727042-727042 (2013-08-13)
The search for new immunopharmacological chemical agents to treat various diseases caused by bacteria, fungi, and protozoa, such as leishmaniasis, for example, has led to the exploration of potential products from plant species and their main active ingredients. Antimonial drugs
Sharon E Jacob et al.
Dermatitis : contact, atopic, occupational, drug, 22(2), 102-105 (2011-04-21)
Compositae-related chemicals cause allergic contact dermatitis (ACD) in children with atopic dermatitis (AD). Moisturizers can be an overlooked exposure source. To evaluate ACD in children with recalcitrant AD and a reported history of intolerance to Aquaphor Healing Ointment (AHO) moisturizer.
Christine Tschiggerl et al.
Plant foods for human nutrition (Dordrecht, Netherlands), 67(2), 129-135 (2012-03-14)
Chamomile (German Chamomile, Matricaria recutita L., Asteraceae) is one of the most popular medicinal plants in use as an herbal tea for food purposes and in folk medicine. Qualitative and semi-quantitative analyses of the volatile fraction of chamomile herbal tea
Nayrton Flávio Moura Rocha et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 44(4), 455-461 (2011-09-20)
This work examined the gastroprotection of (-)-α-bisabolol, an unsaturated optically active sesquiterpene alcohol obtained by the direct distillation essential oil from plants. (-)-α-Bisabolol has been described as a compound capable of reducing the gastric ulcer area in response to absolute

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