142077

2,2,2-Trichloroethyl chloroformate

98%

• Sinonimo/i: 2,2,2-Trichloroethoxycarbonyl chloride
• Formula condensata: ClCOOCH₂CCl₃
• Numero CAS: 17341-93-4
• Peso molecolare: 211.86
• Beilstein: 970619
• Numero CE: 241-363-7
• Numero MDL: MFCD00000810
• Codice UNSPSC: 12352100
• ID PubChem: 24848380
• NACRES: NA.22

Proprietà

• Tensione di vapore: 0.06 psi ( 20 °C)
• Livello qualitativo: 200
• Saggio: 98%
• Stato: liquid
• Indice di rifrazione: n20/D 1.471 (lit.)
• P. ebollizione: 171-172 °C (lit.)
• Densità: 1.539 g/mL at 25 °C (lit.)
• Gruppo funzionale: chloro
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: ClC(=O)OCC(Cl)(Cl)Cl
• InChI: 1S/C3H2Cl4O2/c4-2(8)9-1-3(5,6)7/h1H2; LJCZNYWLQZZIOS-UHFFFAOYSA-N

Descrizione

Descrizione generale

2,2,2-Trichloroethyl chloroformate (TrocCl) serves as a versatile reagent used for selective acylation and dealkylation in organic synthesis. It is used in regio, chemo, and stereoselective synthesis.

Applicazioni

• 2,2,2-Trichloroethyl chloroformate was used as derivatizing reagent in gas chromatographic/mass spectrometric determination of a large range of amphetamine-related drugs and ephedrines in plasma, urine and hair samples.
• It was used as starting reagent during the synthesis of 6-Nor-9,10-dihydrolysergic acid methyl ester.
• It was used as reagent during N-demethylation of dextromethorphan.
• It was used as protecting reagent for aliphatic and aromatic hydroxyl and amino groups.

Protecting reagent for aliphatic and aromatic hydroxyl and amino groups.

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS05
• Avvertenze: Danger
• Indicazioni di pericolo: H314,H331
• Consigli di prudenza: P280 - P303 + P361 + P353 - P304 + P340 + P311 - P305 + P351 + P338 + P310
• Classi di pericolo: Acute Tox. 3 Inhalation - Eye Dam. 1 - Skin Corr. 1B
• Codice della classe di stoccaggio: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter