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03439

Sigma-Aldrich

N-Ethyldiisopropylamine solution

suitable for peptide synthesis, ~2 M in 1-methyl-2-pyrrolidinone

Synonyme(s) :

N,N-Diisopropylethylamine, DIPEA, Hünig’s base

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About This Item

Formule empirique (notation de Hill):
C8H19N
Numéro CAS:
7087-68-5
Poids moléculaire :
129.24
Numéro Beilstein :
4124745
Numéro MDL:
MFCD00008868
Code UNSPSC :
12352100
ID de substance PubChem :
329747633
Nomenclature NACRES :
NA.21

Forme

liquid

Niveau de qualité

100

Concentration

~2 M in 1-methyl-2-pyrrolidinone

Impuretés

≤0.2% water (KFT)

Indice de réfraction

n20/D 1.454

Application(s)

peptide synthesis

Chaîne SMILES 

CCN(C(C)C)C(C)C

InChI

1S/C8H19N/c1-6-9(7(2)3)8(4)5/h7-8H,6H2,1-5H3

Clé InChI

JGFZNNIVVJXRND-UHFFFAOYSA-N

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Catégories apparentées

Description générale

N-Ethyldiisopropylamine (EDIA) reacts with monoactivated Michael acceptors to afford symmetrical sulfones.

Application

N,N-Diisopropylethylamine (DIPEA), also known as Hünig′s base, is a sterically hindered amine. It is commonly employed as a base in peptide synthesis. Additionally, DIPEA is also used in the Pd-catalyzed cross-coupling reactions, which include Heck coupling and Sonagashira coupling reactions.

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Flam. Liq. 3 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

73.4 °F

Point d'éclair (°C)

23 °C

Équipement de protection individuelle

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Certificats d'analyse (COA)

Lot/Batch Number
BCCG7527
BCCC5636
BCCB6845
BCBX8736
BCBX3797

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