SML2906

ERGi-USU

≥98% (HPLC)

• Synonym(e): 1-[2-(2-Thiazolyl)diazenyl]-2-naphthalenol, 1-[2-Thiazolylazo]-2-naphthol, NSC139021, TAN
• Empirische Formel (Hill-System): C₁₃H₉N₃OS
• CAS-Nummer: 1147-56-4
• Molekulargewicht: 255.30
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: faint brown to dark red
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: −20°C
• InChI: 1S/C13H9N3OS/c17-11-6-5-9-3-1-2-4-10(9)12(11)15-16-13-14-7-8-18-13/h1-8,17H
• InChIKey: IOMXCGDXEUDZAK-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

ERGi-USU is a selective and potent inhibitor of growth of ERG positive cancer cell lines, while spearing normal prostate or endothelial cells. It potently inhibits growth of ERG positive VCaP xenografts in mice. ERGi-USU is a potent and selective ligand of the ribosomal atypical kinase RIOK2 (right open reading frame (RIO) kinase 2) that induces ribosomal stress.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3