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Merck

N6505

Sigma-Aldrich

β-Nicotinamidadenin-dinucleotidphosphat-2′-Phosphat, reduziert Tetranatriumsalz

≥95% (HPLC)

Synonym(e):

β-NADPH, 2′-NADPH Hydrat, Coenzym II reduziert Tetranatriumsalz, Dihydronicotinamidadenin-dinucleotidphosphat Tetranatriumsalz, NADPH Na4, TPNH2 Na4

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About This Item

Empirische Formel (Hill-System):
C21H26N7Na4O17P3 · xH2O
CAS-Nummer:
Molekulargewicht:
833.35 (anhydrous basis)
MDL-Nummer:
UNSPSC-Code:
41106305
PubChem Substanz-ID:
NACRES:
NA.51

Qualitätsniveau

Assay

≥95% (HPLC)
≥95% (spectrophotometric assay)

Form

powder

Lagertemp.

−20°C

SMILES String

[Na+].[Na+].[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@H]2O[C@@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](OP([O-])([O-])=O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@H](O)[C@@H]2O

InChI

1S/C21H30N7O17P3.4Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;;;/q;4*+1/p-4/t10-,11+,13-,14+,15-,16+,20-,21+;;;;/m0..../s1

InChIKey

WYWWVJHQDVCHKF-MPUNMZHWSA-J

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Anwendung

β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

Biochem./physiol. Wirkung

NADPH ist ein Elektronenspender und Cofaktor vieler Redox-Enzyme, einschließlich Stickoxid-Synthetase.

Angaben zur Herstellung

Enzymatically reduced.

Sonstige Hinweise

abgefüllt nach Gewicht des Feststoffs

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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