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C3175

Sigma-Aldrich

Chloramphenicol-Water Soluble

powder, suitable for cell culture, BioReagent

Synonym(e):

Chloramphenicol, Chlornitromycin, Chlorocid, Chloromycetin, Cloramfenicol, D-(−)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol, D-(−)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide, Chloromycetin, D-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]aceta, Kloramfenikol

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About This Item

UNSPSC-Code:
12352207
NACRES:
NA.76

product name

Chloramphenicol-Water Soluble, powder, BioReagent, suitable for cell culture

Produktlinie

BioReagent

Form

powder

Methode(n)

cell culture | mammalian: suitable

Löslichkeit

H2O: 50-500 mg/mL (stock solution)
PBS: 50-500 mg/mL (stock solution)
other salt solutions: not recommended

Wirkungsspektrum von Antibiotika

Gram-negative bacteria
Gram-positive bacteria
mycobacteria
mycoplasma

Wirkungsweise

protein synthesis | interferes

Anwendung

Chloramphenicol-Water Soluble has been used:

  • as a supplement in Luria-Bertani (LB) medium to culture Escherichia coli
  • as a supplement in LB agar to culture Citrobacter rodentium
  • to culture Toxoplasma gondii

Biochem./physiol. Wirkung

Chloramphenicol is a natural product found in Streptomyces venezuelae. It shows a broad range of antibiotic activity against Gram-negative and Gram-positive bacteria by binding to the peptidyl transferase loop of the ribosomal RNA to block the peptide bond formation.

Verpackung

Package size based on chloramphenicol

Sonstige Hinweise

Formulated to contain approx. 100 mg chloramphenicol per gram of powder; balance 2-hydroxypropyl-β-cyclodextrin.
Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Keep in a dry place.

Piktogramme

Health hazardCorrosion
GHS08,GHS05

Signalwort

Danger

Gefahreneinstufungen

Carc. 2 - Eye Dam. 1 - Repr. 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type P2 (EN 143) respirator cartridges

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Chloramphenicolpalmitat United States Pharmacopeia (USP) Reference Standard

USP

1107300

Chloramphenicolpalmitat

A Chatzitakis et al.
Water research, 42(1-2), 386-394 (2007-08-19)
The photocatalytic degradation of Chloramphenicol, an antibiotic drug, has been investigated in aqueous heterogeneous solutions containing n-type oxide semiconductors as photocatalysts. The disappearance of the organic molecule follows approximately a pseudo-first-order kinetics according to the Langmuir-Hinshelwood model. It was observed
Taru Hilander et al.
Nucleic acids research, 46(2), 849-860 (2017-12-12)
Accuracy of protein synthesis is enabled by the selection of amino acids for tRNA charging by aminoacyl-tRNA synthetases (ARSs), and further enhanced by the proofreading functions of some of these enzymes for eliminating tRNAs mischarged with noncognate amino acids. Mouse

Artikel

Antibiotic Kill Curve

Antibiotic kill curve is a dose response experiment in which mammalian cells are subjected to increasing amounts of selection antibiotic

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