82669

1-Pyrenbuttersäurehydrazid

for fluorescence, ≥97.0% (T)

• Synonym(e): 4-(1-Pyrenyl)-buttersäure-hydrazid
• Empirische Formel (Hill-System): C₂₀H₁₈N₂O
• CAS-Nummer: 55486-13-0
• Molekulargewicht: 302.37
• MDL-Nummer: MFCD00467260
• UNSPSC-Code: 12352125
• PubChem Substanz-ID: 329769260
• NACRES: NA.32

Eigenschaften

• Qualität: for fluorescence
• Qualitätsniveau: 100
• Assay: ≥97.0% (T)
• Form: solid
• mp (Schmelzpunkt): 167-171 °C
• SMILES String: NNC(=O)CCCc1ccc2ccc3cccc4ccc1c2c34
• InChI: 1S/C20H18N2O/c21-22-18(23)6-2-3-13-7-8-16-10-9-14-4-1-5-15-11-12-17(13)20(16)19(14)15/h1,4-5,7-12H,2-3,6,21H2,(H,22,23)
• InChIKey: SOPPDVMSOKMZOC-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

1-Pyrenebutyric hydrazide (PBH) finds biological/medical applications in the detection, labeling, and quantification of biological carbonyl compounds including aldehydes and/or ketones and carboxylic acids. It is also industrially used in chemo-sensor materials, lubricants, etc.

Anwendung

1-Pyrenebutyric hydrazide may be used as a fluorescence derivatization reagent in the following:

• Determination of succinylacetone (SA) in urine samples of hepatorenal tyrosinemia patients using high-pressure liquid chromatography with fluorescence detection (HPLC-FLD).
• Determination of glutaric and 3-hydroxyglutaric acids in urine of glutaric acidemia type I patients using HPLC technique with intramolecular excimer-forming fluorescence derivatization.

Sonstige Hinweise

Fluoreszierendes Markierungsreagens für Carbonylverbindungen, z.B. Cyclobutanone, die bei der Bestrahlung von Lebensmitteln gebildet werden; Markierung anderer Verbindungen

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302 + H312 + H332 - H315 - H319 - H335
• P-Sätze: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves