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Merck

18079

Millipore

Cycloheximid -Lösung

0.1%, suitable for microbiology

Synonym(e):

CHX

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About This Item

Empirische Formel (Hill-System):
C15H23NO4
CAS-Nummer:
Molekulargewicht:
281.35
MDL-Nummer:
UNSPSC-Code:
41171614
PubChem Substanz-ID:
NACRES:
NA.85

Sterilität

sterile (Filtered and Aseptic Handled)

Qualitätsniveau

Form

liquid

Haltbarkeit

limited shelf life, expiry date on the label

Konzentration

0.1%

Wirkungsspektrum von Antibiotika

fungi

Anwendung(en)

environmental
food and beverages

microbiology

Lagertemp.

2-8°C

Eignung

bacteria

SMILES String

O=C1[C@@]([C@H](O)CC2CC(NC(C2)=O)=O)([H])C[C@@H](C)C[C@@H]1C

InChI

1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1

InChIKey

YPHMISFOHDHNIV-FSZOTQKASA-N

Angaben zum Gen

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Allgemeine Beschreibung

Cycloheximide solution is a selective supplement, that is safer and easier to use than cycloheximide powder. The required volume can be simply added to the medium before or after sterilization.

Anwendung

Cycloheximide solution has been used as a supplement in De Man, Rogosa and Sharpe (MRS) and GM-17 agar plates to study its effects on lactic acid bacteria (LAB).

Biochem./physiol. Wirkung

Cycloheximide solution is used to block the protein synthesis for suppressing the growth of fungi.

Physikalische Form

Steril filtrierte Lösung, enthält 0.1% Cycloheximid

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Xing Wang et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(43), 15438-15443 (2014-10-16)
The receptor-interacting kinase-3 (RIP3) and its downstream substrate mixed lineage kinase domain-like protein (MLKL) have emerged as the key cellular components in programmed necrotic cell death. Receptors for the cytokines of tumor necrosis factor (TNF) family and Toll-like receptors (TLR)
V O Kaminskyy et al.
Cell death & disease, 4, e522-e522 (2013-03-09)
TNF-related apoptosis-inducing ligand (TRAIL) is a promising cytokine for killing tumor cells. However, a number of studies have demonstrated that different cancer cells resist TRAIL treatment and, moreover, TRAIL can promote invasion and metastasis in resistant cells. Here we report
Soma Vignarajan et al.
Oncotarget, 5(15), 6289-6299 (2014-07-16)
Aberrant increase in pAKT, due to a gain-of-function mutation of PI3K or loss-of-function mutation or deletion of PTEN, occurs in prostate cancer and is associated with poor patient prognosis. Cytosolic phospholipase A₂α (cPLA₂α) is a lipid modifying enzyme by catalyzing
Taichi Hara et al.
Scientific reports, 4, 6992-6992 (2014-11-12)
Peripheral myelin protein 22 (PMP22) resides in the plasma membrane and is required for myelin formation in the peripheral nervous system. Many PMP22 mutants accumulate in excess in the endoplasmic reticulum (ER) and lead to the inherited neuropathies of Charcot-Marie-Tooth
Julien Dubrulle et al.
eLife, 4 (2015-04-15)
Morphogen gradients expose cells to different signal concentrations and induce target genes with different ranges of expression. To determine how the Nodal morphogen gradient induces distinct gene expression patterns during zebrafish embryogenesis, we measured the activation dynamics of the signal

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