PIN1
peptidylprolyl cis/trans isomerase, NIMA-interacting 1
Synonyms:
DOD, UBL5
Species:
Human PIN1 (5300), Mouse Pin1 (23988), Rat Pin1 (298696), Thale Cress PIN1 (843693), Zebrafish pin1 (393721), domestic cat PIN1 (101087904), dog PIN1 (484963), chicken PIN1 (100859153), naked mole-rat Pin1 (101708402), domestic guinea pig Pin1 (100726337) ...More
UniProtKB ID:
Gene ID:
- Human(5300) Summary: Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]
- Mouse(23988) protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
- Rat(298696) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
- Thale Cress(843693) auxin efflux carrier component 1
- Zebrafish(393721) protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
- domestic cat(101087904) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
- dog(484963) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
- chicken(100859153) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
- naked mole-rat(101708402) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
- domestic guinea pig(100726337) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
- cow(535470) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
- sheep(101110756) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Pin1 Antibody, clone 5B4.1, clone 5B4.1, from mouse,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot
Anti-PIN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-PIN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-PIN1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
western blot
western blot
Anti-phospho-Pin1 (pSer16) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Cycloheximide solution, Ready-Made Solution, microbial, 100 mg/mL in DMSO, Suitable for cell culture,
Species
human