MABT108

Anti-TNF-alpha induced protein 6 (TSG-6) Antibody, clone NG3

clone NG3, from mouse

• Synonym(e): Tumor necrosis factor-inducible gene 6 protein, TNF-stimulated gene 6 protein, TSG-6, Tumor necrosis factor alpha-induced protein 6, TNF alpha-induced protein 6
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: NG3, monoclonal
• Speziesreaktivität: human, mouse
• Methode(n): ELISA: suitable; western blot: suitable
• Isotyp: IgG2bκ
• NCBI-Hinterlegungsnummer: NP_033424
• UniProt-Hinterlegungsnummer: O08859
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified

Beschreibung

Allgemeine Beschreibung

Tumor Necrosis Factor-alpha (TNF-alpha), also known as TSG-6, is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. The mature form of human TNF-alpha has 157 amino acid residues. TNF-alpha induced protein 6 may be involved in cell-cell and cell-matrix interactions during normal inflammatory responses and during tumorigenesis.

Spezifität

Published to react with human TSG-6 (Nagyeri, G., et al. (2011). JBC. PMID: 21566135).

Immunogen

Epitope: Unknown

GST-tagged recombinant protein corresponding to mouse TSG-6.

Anwendung

Research Category
Zellstruktur

Research Sub Category
ECM-Proteine

Detect TNF-alpha induced protein 6 (TSG-6) using this Anti-TNF alpha Antibody, clone NG3 validated for use in WB, ELISA. This TNF alpha antibody has been tested in Human and Mouse.

ELISA: A previous lot of this antibody was used in capture ELISA to demonstrate a typical standard curve for measuring TSG6 from normal (naïve) serum.

Western Blot Analysis: A previous lot of this antibody was show to detect human or mouse samples (Nagyeri, G., et al. (2011). JBC. PMID: 21566135).

Qualität

Evaluated by Western Blot in mouse ovary tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected TSG-6 in 10 µg of mouse ovary tissue lysate.

Zielbeschreibung

~29 kDa observed.
An uncharacterized band appears at ~50 kDa in some lysates.

Physikalische Form

Protein G Purified

Format: Purified

Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
Mouse ovary tissue lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable