V900422

Ácido fólico

Vetec^™, reagent grade, ≥97%

• Sinônimo(s): PteGlu, Vitamina M, Ácido pteroil-L-glutâmico
• Fórmula empírica (Notação de Hill): C₁₉H₁₉N₇O₆
• Número CAS: 59-30-3
• Peso molecular: 441.40
• Beilstein: 100781
• Número CE: 200-419-0
• Número MDL: MFCD00079305
• Código UNSPSC: 12352106
• ID de substância PubChem: 329829830

Propriedades

• grau: reagent grade
• linha de produto: Vetec^™
• Ensaio: ≥97%
• forma: powder
• técnica(s): HPLC: suitable
• cor: yellow to orange
• pf: >285 °C
• cadeia de caracteres SMILES: NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O
• InChI: 1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
• chave InChI: OVBPIULPVIDEAO-LBPRGKRZSA-N

Descrição

Descrição geral

Folic acid belongs to vitamin B group and is also called as vitamin B₉ or folate. It is present as 5-methyltetrahydrofolate in humans. Grains, fruits and vegetables are dietary sources of folate. Pteroylmonoglutamate is a synthetic folate which comprises single glutamate and exists in the oxidized state.

Ações bioquímicas/fisiológicas

Folic acid is essential for cell growth, brain functioning and plays a key role on serine production from glycine. It also coordinates with vitamin B₁₂ in maintaining iron levels. Deficiency of folate is implicated in megaloblastic anemia. Folic acid aids in the repair and synthesis of DNA. Dietary supplementation and fortification of folate in foods is recommended for pregnant women especially in the first trimester to avoid congenital malformation and neural tube defects (NTDs). However, folate fortification may also impose a moderate risk of developing prostate cancer. Supplementation of folate to colon cancer cells diminishes iron levels and impairs the cell division.

Informações legais

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1