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1650006

USP

Tetracaine hydrochloride

United States Pharmacopeia (USP) Reference Standard

Sinônimo(s):

4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester, Amethocaine hydrochloride

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About This Item

Fórmula empírica (Notação de Hill):
C15H24N2O2 · HCl
Número CAS:
136-47-0
Peso molecular:
300.82
Número MDL:
MFCD00038912
Código UNSPSC:
41116107
ID de substância PubChem:
329751254
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

tetracaine

fabricante/nome comercial

USP

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

cadeia de caracteres SMILES

Cl.CCCCNc1ccc(cc1)C(=O)OCCN(C)C

InChI

1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H,4-5,10-12H2,1-3H3;1H

chave InChI

PPWHTZKZQNXVAE-UHFFFAOYSA-N

Informações sobre genes

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Tetracaine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Benzocaine, Butamben, and Tetracaine Hydrochloride Gel
  • Benzocaine, Butamben, and Tetracaine Hydrochloride Ointment
  • Benzocaine, Butamben, and Tetracaine Hydrochloride Topical Aerosol®
  • Benzocaine, Butamben, and Tetracaine Hydrochloride Topical Solution
  • Lidocaine, Racepinephrine, and Tetracaine Hydrochlorides Compounded Topical Gel
  • Neomycin Sulfate, Isoflupredone Acetate, and Tetracaine Hydrochloride Ointment
  • Neomycin Sulfate, Isoflupredone Acetate, and Tetracaine Hydrochloride Topical Powder
Topical ophthalmic anesthetic; used for spinal anesthesia

Ações bioquímicas/fisiológicas

Blocks voltage-sensitive release of Ca2+ from sarcoplasmic reticulum.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Informações legais

Aerosol is a registered trademark of Cytec Technology Corp.

Pictogramas

Skull and crossbones
GHS06

Palavra indicadora

Danger

Frases de perigo

H301,H319,H336

Classificações de perigo

Acute Tox. 3 Oral - Eye Irrit. 2 - STOT SE 3

Órgãos-alvo

Central nervous system

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Antimicrobial agents and chemotherapy, 58(8), 4380-4383 (2014-05-21)
We have reported significantly higher convulsion prevalence in patients treated with cefepime than in those treated with meropenem. Additionally, cefepime-associated convulsions were found only in patients with brain disorders, not renal failure. Here, we compared the convulsive liability of cefepime
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Investigative ophthalmology & visual science, 55(12), 8371-8376 (2014-12-04)
To compare the occurrence rate and depth of the demarcation line and topographical outcome after corneal cross-linking (CXL) for keratoconus using two different treatment protocols. A retrospective analysis of 131 eyes with progressive keratoconus treated with CXL using riboflavin and
Elisa Cinotti et al.
American journal of ophthalmology, 159(2), 324-333 (2014-12-03)
To evaluate whether the handheld in vivo reflectance confocal microscopy that has been recently developed for the study of skin tumors is suitable for the diagnosis of conjunctival tumors. Prospective study, observational case series. We prospectively evaluated the reflectance confocal
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Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 31(2), 106-113 (2014-11-05)
The aim of the study was to evaluate the effect of 3 subconjunctival bevacizumab injections in patients with an early corneal pterygium recurrence. This study was a nonrandomized single center trial. Patients with an early corneal pterygium recurrence were selected.
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