1642358

Sunitinib malate

United States Pharmacopeia (USP) Reference Standard

• Sinônimo(s): N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioic acid (1:1) salt, SU 011248, SU 11248, SU112248
• Fórmula empírica (Notação de Hill): C₂₂H₂₇FN₄O₂ · C₄H₆O₅
• Número CAS: 341031-54-7
• Peso molecular: 532.56
• Número MDL: MFCD08282795
• Código UNSPSC: 41116107
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• Agency: USP
• família API: sunitinib
• embalagem: pkg of 200 mg
• fabricante/nome comercial: USP
• aplicação(ões): pharmaceutical
• formato: neat
• cadeia de caracteres SMILES: O[C@@H](CC(O)=O)C(O)=O.CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C
• InChI: 1S/C22H27FN4O2.C4H6O5/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28;5-2(4(8)9)1-3(6)7/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28);2,5H,1H2,(H,6,7)(H,8,9)/b17-12-;/t;2-/m.0/s1
• chave InChI: LBWFXVZLPYTWQI-IPOVEDGCSA-N

Descrição

Descrição geral

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Aplicação

Sunitinib malate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Ações bioquímicas/fisiológicas

Sunitinib malate is a receptor tyrosine kinase inhibitor, which targets VEGF-R1, VEGF-R2, VEGF-R3, PDGF-Rα, PDGF-Rβ, KIT, FLT3, CSF-1R, and RET. Sunitinib malate is an anticancer drug.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS08
• Palavra indicadora: Danger
• Frases de perigo: H360,H372
• Declarações de precaução: P202 - P260 - P264 - P280 - P308 + P313 - P405
• Classificações de perigo: Repr. 1B - STOT RE 1 Oral
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable