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Documentos Principais

1589007

USP

Pyrimethamine

United States Pharmacopeia (USP) Reference Standard

Sinônimo(s):

5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine

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About This Item

Fórmula empírica (Notação de Hill):
C12H13ClN4
Número CAS:
Peso molecular:
248.71
Beilstein:
219864
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

pyrimethamine

fabricante/nome comercial

USP

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CCC1=NC(N)=NC(N)=C1C2=CC=C(Cl)C=C2

InChI

1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)

chave InChI

WKSAUQYGYAYLPV-UHFFFAOYSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Pyrimethamine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
  • Pyrimethamine Tablets
  • Sulfadoxine and Pyrimethamine Tablets
  • Pyrimethamine Compounded Oral Suspension

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Declarações de precaução

Classificações de perigo

Acute Tox. 4 Oral

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Lot/Batch Number

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Issaka Sagara et al.
Malaria journal, 13, 358-358 (2014-09-14)
In sub-Saharan Africa, artemisinin-based combination therapy (ACT) and injectable artesunate are the first-line treatments for uncomplicated and severe Plasmodium falciparum malaria, respectively. However, recent studies suggest that delayed anaemia is associated with these treatments in non-immune travellers. This paper aimed
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Drug metabolism and pharmacokinetics, 29(3), 266-271 (2014-01-07)
Telaprevir-based triple therapy is a highly effective treatment for chronic hepatitis C. However, adverse reactions include reversible and dose-dependent elevation of serum creatinine levels. We speculated that this effect reflects inhibition of the renal organic cation transporters hOCT2, hMATE1, and
Sarmad N Mageed et al.
Antimicrobial agents and chemotherapy, 58(11), 6345-6353 (2014-07-23)
Toxoplasma gondii is a major food pathogen and neglected parasitic infection that causes eye disease, birth defects, and fetal abortion and plays a role as an opportunistic infection in AIDS. In this study, we investigated pantothenic acid (vitamin B5) biosynthesis

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