1500218

Paroxetine hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Sinônimo(s): Paroxetine hydrochloride hemihydrate, (3S-trans)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride hemihydrate
• Fórmula empírica (Notação de Hill): C₁₉H₂₀FNO₃ · HCl · .5 H₂O
• Número CAS: 110429-35-1
• Peso molecular: 374.83
• Número MDL: MFCD03658863
• Código UNSPSC: 41116107
• ID de substância PubChem: 329750674
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• família API: paroxetine
• fabricante/nome comercial: USP
• aplicação(ões): pharmaceutical (small molecule)
• formato: neat
• cadeia de caracteres SMILES: O.Cl[H].Fc1ccc(cc1)[C@@H]2CCNC[C@H]2COc3ccc4OCOc4c3
• InChI: 1S/C19H20FNO3.ClH.H2O/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;;/h1-6,9,14,17,21H,7-8,10-12H2;1H;1H2/t14-,17-;;/m0../s1
• chave InChI: QRQSGFFISBKLMZ-YHOFXEKLSA-N
• Informações sobre genes: human ... SLC6A4(6532)

Descrição

Descrição geral

Paroxetine hydrochloride is a phenylpiperidine derivative which is selective serotonin reuptake inhibitor. The protein binding ability is high. It has 2 forms, non-hygroscopic hemihydrate and hygroscopic anhydrate. This drug is seen useful in treating premature ejaculation in men.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Paroxetine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Ações bioquímicas/fisiológicas

Paroxetine hydrochloride hemihydrate is one of the most potent and selective of the selective serotonin reuptake inhibitors (SSRI); antidepressant

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS07,GHS09
• Palavra indicadora: Warning
• Frases de perigo: H302,H317,H319,H335,H410
• Declarações de precaução: P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable