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Key Documents

1437450

USP

Methyl salicylate

United States Pharmacopeia (USP) Reference Standard

Sinônimo(s):

2-Hydroxybenzoic acid methyl ester, Methyl 2-hydroxybenzoate, Oil of wintergreen, Wintergreen oil

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About This Item

Fórmula linear:
2-(HO)C6H4CO2CH3
Número CAS:
Peso molecular:
152.15
Beilstein:
971516
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

pharmaceutical primary standard

densidade de vapor

5.26 (vs air)

pressão de vapor

1 mmHg ( 54 °C)

família API

methyl salicylate

temperatura de autoignição

847 °F

fabricante/nome comercial

USP

índice de refração

n20/D 1.536 (lit.)

pb

222 °C (lit.)

pf

−8-−7 °C (lit.)

densidade

1.174 g/mL at 25 °C (lit.)

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

cadeia de caracteres SMILES

COC(=O)c1ccccc1O

InChI

1S/C8H8O3/c1-11-8(10)6-4-2-3-5-7(6)9/h2-5,9H,1H3

chave InChI

OSWPMRLSEDHDFF-UHFFFAOYSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Methyl salicylate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Repr. 2 - Skin Sens. 1B

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

204.8 °F - closed cup

Ponto de fulgor (°C)

96 °C - closed cup


Certificados de análise (COA)

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T Y Chan
Human & experimental toxicology, 15(9), 747-750 (1996-09-01)
Methyl salicylate (oil of wintergreen) is widely available in many over-the-counter liniments, ointments, lotions or medicated oils for the relief of musculoskeletal aches and pains. Ingestion of methyl salicylate poses the threat of severe, rapid-onset salicylate poisoning because of its
A Lapczynski et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 45 Suppl 1, S428-S452 (2007-11-23)
A toxicologic and dermatologic review of methyl salicylate when used as a fragrance ingredient is presented.
Jonathan E Davis
The Journal of emergency medicine, 32(1), 63-69 (2007-01-24)
Serious toxicity can result from exposure to small amounts of methyl salicylate. Methyl salicylate is widely available as a component in many over-the-counter brands of creams, ointments, lotions, liniments and medicated oils intended for topical application to relieve musculoskeletal aches
Taraka R Donti et al.
Disease models & mechanisms, 7(2), 271-280 (2013-11-26)
Mutations in subunits of succinyl-CoA synthetase/ligase (SCS), a component of the citric acid cycle, are associated with mitochondrial encephalomyopathy, elevation of methylmalonic acid (MMA), and mitochondrial DNA (mtDNA) depletion. A FACS-based retroviral-mediated gene trap mutagenesis screen in mouse embryonic stem
Wen-Po Chuang et al.
The New phytologist, 201(3), 928-939 (2013-12-07)
Some plant-derived anti-herbivore defensive proteins are induced by insect feeding, resist digestion in the caterpillar gut and are eliminated in the frass. We have identified several maize proteins in fall armyworm (Spodoptera frugiperda) frass that potentially play a role in

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