50137-U

LiChrospher^® RP-18 (5 µm) HPLC Columns

L × I.D. 25 cm × 4 mm, HPLC Column

• Sinônimo(s): TM=["LiChrospher"] C18 HPLC column
• Código UNSPSC: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

Propriedades

• Nome do produto: LiChrospher^® RP-18 HPLC Column, 5 μm particle size, L × I.D. 25 cm × 4 mm
• Materiais: stainless steel column
• Agency: suitable for USP L1
• linha de produto: LiChrospher^®
• Características: endcapped: no
• fabricante/nome comercial: LiChrospher^®
• embalagem: 1 ea of
• Extensão da rotulagem: 21% Carbon loading
• Parâmetros: ≤70 °C temp. range; 400 bar pressure (5801 psi)
• técnica(s): HPLC: suitable
• C × D.I.: 25 cm × 4 mm
• área da superfície: 350 m²/g
• Matriz: octadecyl; silica particle platform; fully porous particle
• Grupo ativo da matriz: C18 (octadecyl) phase
• tamanho de partícula: 5 μm
• tamanho de poro: 100 Å
• pH operacional: 2-7.5
• aplicação(ões): food and beverages
• técnica de separação: reversed phase

Descrição

Descrição geral

LiChrospher^® RP-18 HPLC column (L × I.D. 25 cm × 4 mm) is found to be reliable and high versatile. Suitable for reversed-phase high performance liquid chromatography (RP-HPLC) of acidic, neutral and weakly basic compounds, according to L1 USP specifications.

Aplicação

• HPLC-UV and GC-MS Methods for Determination of Chlorambucil and Valproic Acid in Plasma for Further Exploring a New Combined Therapy of Chronic Lymphocytic Leukemia.: This study developed and validated HPLC-UV and GC-MS methods for determining chlorambucil and valproic acid in plasma, aiming to explore their combined therapy for chronic lymphocytic leukemia. The LiChrospher^® RP-18 HPLC Column was instrumental in achieving the separation and quantification (Lipska et al., 2021).


• Rapid Determination of Metronidazole and 2-Hydroxymetronidazole in Murine Blood Plasma.: This research utilized the LiChrospher^® RP-18 HPLC Column for the rapid determination of metronidazole and its metabolite in murine blood plasma, highlighting its effectiveness in pharmacokinetic studies (Zemanová et al., 2022).


• Application of chemometric approach for development and validation of high performance liquid chromatography method for estimation of ropinirole hydrochloride.: This paper presents a chemometric approach to developing and validating an HPLC method for estimating ropinirole hydrochloride, utilizing the LiChrospher^® RP-18 column for precise and accurate results (Fatima et al., 2019).


• A New Solid-Phase Extraction Method for Determination of Pantoprazole in Human Plasma Using High-Performance Liquid Chromatography.: The study developed a novel solid-phase extraction method for determining pantoprazole in human plasma using HPLC with the LiChrospher^® RP-18 column, achieving high sensitivity and specificity (Zendelovska et al., 2019).


• Application of an HPLC-MS/MS method for Teicoplanin drug substance and related impurities, part 2: Identity assignment of related impurities.: This research employed the LiChrospher^® RP-18 column in an HPLC-MS/MS method to identify and assign related impurities in teicoplanin drug substances, demonstrating the column′s capability in impurity profiling (Tengattini et al., 2019).

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Informações legais

LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable