Pular para o conteúdo
Merck
Todas as fotos(1)

Key Documents

47864

Supelco

Nicotinic acid

analytical standard

Sinônimo(s):

3-Picolinic acid, Niacin, Pellagra preventive factor, Pyridine-3-carboxylic acid, Vitamin B3

Faça loginpara ver os preços organizacionais e de contrato


About This Item

Fórmula empírica (Notação de Hill):
C6H5NO2
Número CAS:
Peso molecular:
123.11
Beilstein:
109591
Número CE:
Número MDL:
Código UNSPSC:
12164500
ID de substância PubChem:

grau

analytical standard

Nível de qualidade

Certificado de análise (CofA)

current certificate can be downloaded

Características

standard type water soluble vitamin

embalagem

ampule of 1000 mg

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

pf

236-239 °C (lit.)

densidade

1.473 g/cm3 at 25 °C

aplicação(ões)

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

formato

neat

temperatura de armazenamento

2-30°C

cadeia de caracteres SMILES

OC(=O)c1cccnc1

InChI

1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)

chave InChI

PVNIIMVLHYAWGP-UHFFFAOYSA-N

Informações sobre genes

human ... CYP1A2(1544)
rat ... Chrnb2(54239)

Procurando produtos similares? Visita Guia de comparação de produtos

Descrição geral

Nicotinic acid acts as an antilipolytic drug in adipose tissue, and is commonly used for hyperlipoproteinaemia and pellagra.
Nicotinic acid is a water soluble, vitamin belonging to B complex group of vitamins, which can be used as a broad spectrum lipid lowering drug. Its mode of action basically involves the inhibition of the hormone-sensitive triglyceride lipase and thereby, decreasing the lipolysis in adipose tissue.

Aplicação

Nicotinic acid may be used as an analytical reference standard for the quantification of the analyte in tablet dosage forms using reversed-phase high-performance liquid chromatography technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Eye Irrit. 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

379.4 °F - closed cup

Ponto de fulgor (°C)

193 °C - closed cup

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves


Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number

Não está vendo a versão correta?

Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 2

1 of 2

PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect
Tunaru S, et al.
Nature Medicine, 9, 352-352 (2003)
Molecular identification of nicotinic acid receptor
Soga T, et al.
Biochemical and Biophysical Research Communications, 303, 364-369 (2003)
Nicotinic acid: the broad?spectrum lipid drug. A 50th anniversary review
Carlson.A.L
J. Int. Med., 258, 94-114 (2005)
RP-HPLC method for the determination of atorvastatin calcium and nicotinic acid in combined tablet dosage form
Shah DA, et al.
Indian Journal of Pharmaceutical Sciences, 69(5), 700-700 (2007)
Beat Müller et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 20(2), 181-195 (2003-10-11)
A novel methodology for establishing a pharmacological dose-effect relationship of methyl nicotinate, hexyl nicotinate and nicotinic acid acting as peripheral vasodilators in the skin following topical application is investigated. This methodology involves the estimation of the unbound drug concentration in

Artigos

Pyridoxine hydrochloride, ≥98% (HPLC); Nicotinamide, ≥98.5% (HPLC); Thiamine hydrochloride, reagent grade, ≥99% (HPLC); Biotin, ≥99.0% (T); Folic acid, analytical standard; Cyanocobalamin (B12), analytical standard; Riboflavin (B2), analytical standard

Protocolos

Separation of Pyridoxine; Nicotinamide; Nicotinic acid; Folic acid; (−)-Riboflavin, meets USP testing specifications; L-Ascorbic acid

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica