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Astec® CHIROBIOTIC® V2 Chiral HPLC Column

5 μm particle size, L × I.D. 15 cm × 2.1 mm

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About This Item

Código UNSPSC:
41115700
eCl@ss:
32110501
NACRES:
SB.52

Materiais

stainless steel column

Nível de qualidade

Agency

suitable for USP L88

descrição

HPLC column

linha de produto

Astec®

embalagem

pkg of 1 ea

fabricante/nome comercial

Astec®

Parâmetros

0-45 °C temperature
241 bar pressure (3500 psi)

técnica(s)

HPLC: suitable
LC/MS: suitable

C × D.I.

15 cm × 2.1 mm

matriz

High-purity silica gel particle platform
fully porous particle

Grupo ativo da matriz

vancomycin phase

tamanho de partícula

5 μm

tamanho de poro

200 Å

operating pH range

3.5-7.0

técnica de separação

chiral

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Descrição geral

Neutral molecules, amides, acids, esters and amines show considerable enantioselectivity on these vancomycin-based CSPs. A wide variety of secondary and tertiary amines have been separated on the CHIROBIOTIC® V in the polar ionic mode. The CHIROBIOTIC® V has demonstrated many of the separation characteristics of protein-based stationary phases, but with exceptional stability and much higher sample capacity. Some chiral analytes have been resolved that have not been reported separated on any other chiral stationary phase. CHIROBIOTIC® V and V2 differ in their bonding chemistry the pore size of the support particle, giving them different selectivity and preparative capacity.

  • Bonded phase: Vancomycin
  • Operating pH range: 3.5 - 7.0
  • Particle diameter: 5, 10 or 16 μm
  • Pore size: 100 Å (CHIROBIOTIC® V) or 200 Å (CHIROBIOTIC® V2)

CHIROBIOTIC FAQs
CHIROBIOTIC Reference Bibliography
Chiral Product Literature

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Informações legais

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

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Chromatography Liquid Chiral Separations
Xiao, T.L., et al.
Encyclopedia of Separation Science, 1-15 (2000)
Enantioselective and sensitive determination of carvedilol in human plasma using chiral stationary-phase column and reverse-phase liquid chromatography with tandem mass spectrometry
Jiang, Juanjuan, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 960, 92-97 (2014)
Enantioselective determination of doxazosin in human plasma by liquid chromatography?tandem mass spectrometry using ovomucoid chiral stationary phase
Liu, Ke, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 878 (26), 2415-2420 (2010)
Quantitative determination of ondansetron in human plasma by enantioselective liquid chromatography-tandem mass spectrometry
Liu, Ke, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 864 (1-2), 129-136 (2008)
Validation of a chiral liquid chromatography?tandem mass spectrometry method for the determination of pantoprazole in dog plasma
Chen, Meixia, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 906, 85-90 (2012)

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